Gene: TRIM36
Official Full Name: tripartite motif containing 36provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13063 | TRIM36 Knockout cell line (HeLa) | Human | TRIM36 | 1:3~1:6 | Negative | Online Inquiry |
KO13064 | TRIM36 Knockout cell line (HCT 116) | Human | TRIM36 | 1:2~1:4 | Negative | Online Inquiry |
KO13065 | TRIM36 Knockout cell line (HEK293) | Human | TRIM36 | 1:3~1:6 | Negative | Online Inquiry |
KO13066 | TRIM36 Knockout cell line (A549) | Human | TRIM36 | 1:3~1:4 | Negative | Online Inquiry |
TRIM36 Gene Knockout Cell Lines represent a powerful tool in molecular biology, specifically designed to facilitate the study of the TRIM36 gene's functions within cellular pathways. TRIM36, a member of the tripartite motif (TRIM) family of proteins, is implicated in various physiological processes, including immune response regulation and regulation of cellular proliferation. These knockout cell lines provide researchers with a precise genetic model to investigate the consequences of TRIM36 gene elimination, thereby elucidating its role in gene regulation and disease mechanisms.
The primary function of TRIM36 Gene Knockout Cell Lines lies in their ability to enable functional studies by removing the TRIM36 gene, allowing researchers to observe phenotypic changes and downstream effects on signaling pathways. By employing techniques such as CRISPR-Cas9 or RNA interference, these cell lines exhibit complete ablation of TRIM36 expression, offering a reliable platform for investigating its interactions with other proteins, its influence on the cell cycle, and its potential contributions to pathologies such as cancer and autoimmune disorders.
Scientifically, the TRIM36 Gene Knockout Cell Lines hold immense significance for both research and clinical applications. In research settings, these models can accelerate the discovery of therapeutic targets by revealing how TRIM36 modulates key cellular processes. Additionally, understanding TRIM36's role in diseases can pave the way for developing innovative treatments and precision medicine strategies tailored to conditions where TRIM36 is dysregulated.
Compared to alternative products that might utilize transient knockdown approaches or less definitive gene editing techniques, our TRIM36 Gene Knockout Cell Lines offer consistent and stable gene disruption. This stability is crucial for long-term experiments and collaborative studies, ensuring reproducibility and accuracy in experimental outcomes.
For researchers and clinicians seeking to gain deeper insights into gene function and its implications for human health, TRIM36 Gene Knockout Cell Lines are an invaluable resource. They not only enhance our understanding of gene-specific pathways but also contribute to the broader goal of advancing therapeutic interventions. Our company, renowned for its commitment to quality and innovation in biotechnological products, delivers these knockout cell lines with a strong emphasis on rigorous validation and customer support, reinforcing our expertise in providing essential tools for cutting-edge research.
Please note that all services are for research use only. Not intended for any clinical use.
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