Gene: TRIM14
Official Full Name: tripartite motif containing 14provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO07180 | TRIM14 Knockout cell line (HeLa) | Human | TRIM14 | 1:3~1:6 | Negative | Online Inquiry |
KO07181 | TRIM14 Knockout cell line (HCT 116) | Human | TRIM14 | 1:2~1:4 | Negative | Online Inquiry |
KO07182 | TRIM14 Knockout cell line (HEK293) | Human | TRIM14 | 1:3~1:6 | Negative | Online Inquiry |
KO07183 | TRIM14 Knockout cell line (A549) | Human | TRIM14 | 1:3~1:4 | Negative | Online Inquiry |
TRIM14 Gene Knockout Cell Lines are genetically engineered cell lines designed to specifically disrupt the expression of the TRIM14 gene, which encodes a protein involved in various cellular processes, including immune response, cell proliferation, and apoptosis. These knockout cell lines serve as powerful tools for researchers investigating the functional implications of TRIM14 deficiency in different biological contexts.
The primary mechanism by which TRIM14 Gene Knockout Cell Lines operate is through the introduction of targeted mutations that effectively silence the gene, allowing researchers to study the downstream effects of its absence. By understanding how the loss of TRIM14 influences cellular signaling pathways, gene expression, and overall cellular function, scientists can glean insights into its role in disease mechanisms, particularly in inflammatory responses and cancer biology.
The scientific importance of these knockout cell lines cannot be overstated, as they provide a unique opportunity to model human diseases in vitro, facilitating the exploration of therapeutic targets and the testing of novel drugs. In clinical research, these models can help identify potential biomarkers and therapeutic strategies, ultimately contributing to the development of personalized medicine approaches.
What sets TRIM14 Gene Knockout Cell Lines apart from other genetic models is the precision of their design and the robustness of their performance in various experimental settings. They offer high reproducibility and consistency, making them essential for both basic and applied research. Additionally, their use can significantly reduce the time and costs associated with developing and characterizing new models from scratch.
For researchers and clinicians, these knockout cell lines hold immense value as they open avenues for groundbreaking discoveries in gene function and disease pathology. The ability to elucidate the role of TRIM14 in a controlled environment enables a deeper understanding of its potential as a therapeutic target.
At [Company Name], we pride ourselves on our commitment to advancing biomedical research through innovative genetic products. Our expertise in developing high-quality cell lines ensures that researchers have access to reliable and effective tools that can accelerate their discoveries and improve their research outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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