Gene: TRIM13
Official Full Name: tripartite motif containing 13provided by HGNC
Gene Summary: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32152 | TRIM13 Knockout cell line (HeLa) | Human | TRIM13 | 1:3~1:6 | Negative | Online Inquiry |
KO32153 | TRIM13 Knockout cell line (HCT 116) | Human | TRIM13 | 1:2~1:4 | Negative | Online Inquiry |
KO32154 | TRIM13 Knockout cell line (HEK293) | Human | TRIM13 | 1:3~1:6 | Negative | Online Inquiry |
KO32155 | TRIM13 Knockout cell line (A549) | Human | TRIM13 | 1:3~1:4 | Negative | Online Inquiry |
TRIM13 Gene Knockout Cell Lines are specially designed cellular models that have undergone genetic modification to delete the TRIM13 gene, which encodes the protein TRIM13 or 'tripartite motif-containing 13.' The TRIM13 protein is implicated in several critical biological processes, including immune regulation, cellular differentiation, and the response to viral infections. By utilizing these knockout cell lines, researchers can precisely dissect the role of TRIM13 in cellular pathways and its contributions to various pathophysiological conditions.
These knockout cell lines function through the precise ablation of TRIM13 expression, allowing for comprehensive studies of its involvement in cellular mechanisms such as the antiviral response and apoptotic signaling. The absence of TRIM13 can reveal insights into cellular behavior and responses under stress or disease states, which are invaluable for both fundamental research and therapeutic development.
From a scientific perspective, TRIM13 Gene Knockout Cell Lines are crucial in elucidating the gene's role in cancer biology, immunology, and infectious diseases. They provide an essential tool for studying disease mechanisms, screening potential therapeutic compounds, and validating drug targets in a controlled environment. Their applications stretch from basic research to translational studies in clinical settings, making them indispensable for laboratories focused on gene function and disease modeling.
What sets TRIM13 Gene Knockout Cell Lines apart from traditional models is their specificity and reliability in selectively removing the target gene without off-target effects commonly associated with other gene-editing techniques. This high specificity ensures that researchers obtain consistent and reproducible results, thereby accelerating the path to new discoveries.
For researchers and clinicians invested in cutting-edge studies of gene function and disease mechanisms, TRIM13 Gene Knockout Cell Lines represent a significant advancement in available biological tools. These lines not only enhance the precision of experimental designs but also facilitate meaningful insights that can progress understanding and treatment of diseases.
As a leader in the field of genetic models, our company prides itself on providing high-quality, validated products that empower scientists to make groundbreaking advancements in research and medicine. Trust in our expertise to deliver exceptional biological products tailored to enhance your research outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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