Gene: TREX2
Official Full Name: three prime repair exonuclease 2provided by HGNC
Gene Summary: This gene encodes a nuclear protein with 3' to 5' exonuclease activity. The encoded protein participates in double-stranded DNA break repair, and may interact with DNA polymerase delta. [provided by RefSeq, Nov 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31062 | TREX2 Knockout cell line (HeLa) | Human | TREX2 | 1:3~1:6 | Negative | Online Inquiry |
KO31063 | TREX2 Knockout cell line (HCT 116) | Human | TREX2 | 1:2~1:4 | Negative | Online Inquiry |
KO31064 | TREX2 Knockout cell line (HEK293) | Human | TREX2 | 1:3~1:6 | Negative | Online Inquiry |
TREX2 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to provide comprehensive insights into the biological functions of the TREX2 gene, which encodes a cytoplasmic 3’ flaps endonuclease that is crucial for DNA repair and cellular responses to stress. This innovative product serves as an invaluable tool for researchers investigating the roles of TREX2 in various pathological conditions, including cancer and genetic disorders, allowing for in-depth mechanistic studies.
The primary function of these cell lines is to facilitate the analysis of the consequences of TREX2 deficiency. By employing CRISPR/Cas9 gene-editing technology, our TREX2 gene knockout cell lines permit the precise disruption of the TREX2 gene, enabling researchers to observe changes in cellular behavior, DNA repair processes, and cell cycle kinetics. This model is instrumental for elucidating the gene’s role in maintaining genomic stability and its implications in disease progression.
In terms of scientific significance, TREX2 Gene Knockout Cell Lines are highly applicable in research focused on genomic integrity, cellular response to DNA damage, and therapeutic interventions in oncology. They provide a relevant platform for testing novel compounds that target DNA repair pathways, making these cell lines crucial in preclinical drug development.
The advantages of our TREX2 Gene Knockout Cell Lines over alternative models include validated and reproducible knockout efficiency, a user-friendly application process, and the support of comprehensive product documentation that aids researchers in experimental design. Unlike other models that may require extensive modifications or lack specific phenotypic characteristics, our cell lines offer streamlined functionality enabling quicker turnaround times for experimental results.
These products hold significant value for researchers and clinicians aiming to unlock the molecular mechanisms behind TREX2-related pathologies. By utilizing our gene knockout cell lines, users can accelerate their research findings while contributing to the broader understanding of the role of DNA repair in human health.
Our company prides itself on expertise in genetic engineering and a commitment to advancing biological research tools. We strive to equip scientists with the highest quality products and technical support necessary for groundbreaking discoveries in molecular biology and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.