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TRAK2 Knockout Cell Lines

Gene: TRAK2

Official Full Name: trafficking kinesin protein 2provided by HGNC

Gene Summary: Predicted to enable GABA receptor binding activity and myosin binding activity. Predicted to be involved in several processes, including mitochondrion distribution; organelle transport along microtubule; and protein O-linked glycosylation. Predicted to be located in cytoplasm; nucleus; and plasma membrane. Predicted to be active in cytoplasmic vesicle; dendrite; and mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00396 TRAK2 Knockout cell line (HeLa) Human TRAK2 1:3~1:6 Negative Online Inquiry
KO13083 TRAK2 Knockout cell line (HCT 116) Human TRAK2 1:2~1:4 Negative Online Inquiry
KO13084 TRAK2 Knockout cell line (HEK293) Human TRAK2 1:3~1:6 Negative Online Inquiry
KO13085 TRAK2 Knockout cell line (A549) Human TRAK2 1:3~1:4 Negative Online Inquiry

Background

TRAK2 Gene Knockout Cell Lines are engineered cellular models specifically designed to study the function of the TRAK2 gene, a critical component involved in mitochondrial trafficking and cellular signaling pathways. By utilizing CRISPR-Cas9 gene-editing technology, these cell lines provide researchers with a powerful tool to investigate the phenotypic consequences of TRAK2 gene deletion or mutation, enabling greater understanding of its role in neurodegenerative diseases and metabolic disorders.

The key mechanism of action revolves around the precise knockout of the TRAK2 gene, which allows scientists to observe the resulting effects on cellular processes, particularly those related to mitochondrial transport and energy production. This can elucidate the gene's involvement in pathological conditions where mitochondrial dysfunction is a hallmark. The TRAK2 knockout cell lines can serve as standardized models for high-throughput screening assays, drug discovery, and the elucidation of disease mechanisms, proving invaluable in both academic research and therapeutic development.

These cell lines stand out due to their specificity and reproducibility, allowing for consistent experimentation across different labs. Compared to traditional cell models that may exhibit background expression of TRAK2, these knockout lines provide a definitive environment to study the absence of this gene. Additionally, they are compatible with various downstream applications such as protein interaction studies, metabolic assays, and gene expression analysis.

For researchers and clinicians focusing on mitochondrial biology and its implications in health and disease, the TRAK2 Gene Knockout Cell Lines offer a unique advantage by providing a reliable and validated model to dissect the intricacies of this crucial gene. Investing in these cell lines not only enhances experimental rigor but also expedites the journey toward potential therapeutic interventions.

As a leader in biotechnological innovations, our company is dedicated to delivering advanced research tools like the TRAK2 Gene Knockout Cell Lines, ensuring that scientists have access to high-quality products that push the boundaries of current biological research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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