Home / TRAK1 Knockout Cell Lines

TRAK1 Knockout Cell Lines

Gene: TRAK1

Official Full Name: trafficking kinesin protein 1provided by HGNC

Gene Summary: Predicted to enable GABA receptor binding activity and myosin binding activity. Involved in endosome to lysosome transport. Located in early endosome and mitochondrion. Implicated in developmental and epileptic encephalopathy 68. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00438 TRAK1 Knockout cell line (HeLa) Human TRAK1 1:3~1:6 Negative Online Inquiry
KO30135 TRAK1 Knockout cell line (HCT 116) Human TRAK1 1:2~1:4 Negative Online Inquiry
KO30136 TRAK1 Knockout cell line (HEK293) Human TRAK1 1:3~1:6 Negative Online Inquiry
KO30137 TRAK1 Knockout cell line (A549) Human TRAK1 1:3~1:4 Negative Online Inquiry

Background

TRAK1 Gene Knockout Cell Lines are state-of-the-art cellular tools specifically engineered to facilitate the study of the TRAK1 gene's role in cellular processes. TRAK1 is a key gene implicated in the regulation of mitochondrial transport and cellular signaling pathways critical for homeostasis and neurodevelopment. These knockout cell lines have been meticulously developed using CRISPR-Cas9 technology to ensure the complete disruption of the TRAK1 gene, providing researchers with a robust system to investigate its function and the biological consequences of its loss.

The primary mechanism of action of TRAK1 knockout cell lines involves the elimination of TRAK1 protein expression, which disrupts the transport of mitochondria along microtubules and may lead to altered energy metabolism and cellular signaling. By utilizing these cell lines, researchers can delve into the implications of TRAK1 activity in various diseases, particularly those related to neurodegeneration and metabolic disorders, thus greatly enhancing our understanding of potential therapeutic targets.

In terms of scientific relevance, TRAK1 Gene Knockout Cell Lines serve as invaluable resources in academic and clinical research settings, enabling in-depth studies on mitochondrial dynamics, neuronal integrity, and cell survival pathways. Their specific design offers unparalleled precision in gene editing, ensuring that researchers can obtain reproducible results in experiments aimed at elucidating the multifaceted roles of TRAK1.

Unlike alternative methods, such as RNA interference, which can produce variable knockdown efficiencies, these knockout cell lines achieve definitive gene inactivation, translating to high confidence in experimental outcomes. Additionally, the time-efficient and cost-effective nature of using established cell lines allows for swift integration into ongoing research projects.

For researchers and clinicians invested in the quest to unlock the complexities of cellular mechanisms, TRAK1 Gene Knockout Cell Lines represent a powerful ally. Their inherently defined genetic background coupled with the validation of their knockout status enhances the reliability of research findings, accelerating the path toward discovery and potential therapeutic interventions. Our company specializes in offering high-quality, genetically modified cell lines and has a proven track record of innovation in the field, ensuring that our products meet the rigorous demands of contemporary biological research.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.