Home / TRAF7 Knockout Cell Lines

TRAF7 Knockout Cell Lines

Gene: TRAF7

Official Full Name: TNF receptor associated factor 7provided by HGNC

Gene Summary: Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.[supplied by OMIM, Apr 2004]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03425 TRAF7 Knockout cell line (HeLa) Human TRAF7 1:3~1:6 Negative Online Inquiry
KO03426 TRAF7 Knockout cell line (HCT 116) Human TRAF7 1:2~1:4 Negative Online Inquiry
KO03427 TRAF7 Knockout cell line (HEK293) Human TRAF7 1:3~1:6 Negative Online Inquiry
KO03428 TRAF7 Knockout cell line (A549) Human TRAF7 1:3~1:4 Negative Online Inquiry

Background

TRAF7 Gene Knockout Cell Lines are engineered cellular models specifically designed to study the functional impact of TRAF7 (TNF Receptor Associated Factor 7) gene deletion. These cell lines have been meticulously crafted through CRISPR-Cas9 genome editing techniques to provide researchers with a flexible platform for investigating the biological pathways and molecular mechanisms associated with TRAF7-related processes, including immune response, cellular signaling, and oncogenesis.

The primary function of these knockout cell lines is to allow for the examination of the consequences of TRAF7 gene disruption, facilitating the exploration of its role in various disease states. By utilizing these models, scientists can observe changes in signal transduction pathways, gene expression profiles, and cellular phenotypes, which can provide insights into the molecular underpinnings of pathologies associated with TRAF7, such as certain cancers and autoimmune disorders.

The scientific importance of TRAF7 Gene Knockout Cell Lines extends to their applications in both fundamental research and clinical settings. They are invaluable tools for drug discovery, enabling researchers to screen for potential therapeutic compounds and elucidate the mechanisms of response in cells lacking TRAF7 expression. Moreover, these models can support biomarker discovery efforts, offering a route to identify novel targets for therapeutic intervention.

Compared to traditional cell lines, TRAF7 Gene Knockout Cell Lines offer unique advantages such as precise gene editing, high reproducibility, and the ability to mimic pathological conditions more accurately. Unlike standard cell lines that might display variable expression levels or pathways, these knockout lines provide a consistent background for experimental analysis, fostering reliable data generation.

For researchers and clinicians, the ability to probe the effects of gene knockout systems enhances experimental rigor and expands the range of investigational questions. This product not only empowers users with state-of-the-art tools for translational research but also reflects our commitment to advancing the field of genetic and cellular biology.

With extensive expertise in developing high-quality research products, our company is dedicated to providing solutions that enhance scientific discovery and drive innovation in the biological sciences. The TRAF7 Gene Knockout Cell Lines stand as a testament to our unwavering commitment to supporting the research community with precisely engineered resources.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.