Gene: TRAF3IP1
Official Full Name: TRAF3 interacting protein 1provided by HGNC
Gene Summary: The protein encoded by this gene interacts with TNF receptor-associated factor 3, tethering it to cytoskeletal microtubules. The encoded protein is also an inhibitor of the innate type I IFN response. Defects in this gene are a cause of Senior-Loken syndrome 9. [provided by RefSeq, Mar 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28257 | TRAF3IP1 Knockout cell line (HeLa) | Human | TRAF3IP1 | 1:3~1:6 | Negative | Online Inquiry |
KO28258 | TRAF3IP1 Knockout cell line (HCT 116) | Human | TRAF3IP1 | 1:2~1:4 | Negative | Online Inquiry |
KO28259 | TRAF3IP1 Knockout cell line (HEK293) | Human | TRAF3IP1 | 1:3~1:6 | Negative | Online Inquiry |
KO28260 | TRAF3IP1 Knockout cell line (A549) | Human | TRAF3IP1 | 1:3~1:4 | Negative | Online Inquiry |
TRAF3IP1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the TRAF3IP1 gene, also known as TNF Receptor-Associated Factor 3 Interacting Protein 1. This gene plays a crucial role in various cellular processes, including immune response, inflammation, and apoptosis. By creating knockout cell lines, researchers can efficiently study the function of TRAF3IP1 in health and disease, thereby unraveling its contributions to cellular signaling pathways and disease mechanisms.
These cell lines offer the unique capability to elucidate the role of TRAF3IP1 within the context of specific experimental conditions. The knockout mechanism is achieved through CRISPR-Cas9 technology, which ensures precise gene editing, resulting in a complete absence of TRAF3IP1 expression. This specificity enables scientists to conduct comparative analyses of normal and TRAF3IP1-deficient cells, providing insights into its signaling pathways and downstream effects on cell behavior, such as proliferation, differentiation, and immune response.
The scientific significance of TRAF3IP1 Gene Knockout Cell Lines extends into multiple fields, including immunology, cancer research, and drug development. These models can be used to investigate TRAF3IP1's involvement in autoimmune diseases or to test the efficacy of therapeutic interventions targeting inflammatory pathways. Researchers can employ these cell lines to validate hypotheses regarding the role of TRAF3IP1, thus enhancing the understanding of disease mechanisms that could lead to novel treatment strategies.
Compared to traditional methods like RNA interference, TRAF3IP1 Gene Knockout Cell Lines provide a more permanent solution for studying gene function, allowing for long-term experiments and more reliable results. This advanced model facilitates higher reproducibility and reproducibility in research, making it a superior alternative.
For researchers and clinicians, the availability of TRAF3IP1 Gene Knockout Cell Lines represents a valuable tool not only for academic research but also for the potential translation of laboratory findings into clinical applications. The ability to model disease states more accurately can lead to greater insights that are directly applicable to patient care.
Our company possesses extensive expertise in genetic engineering and cell line development, ensuring that TRAF3IP1 Gene Knockout Cell Lines are produced to the highest standards of quality and precision. We are committed to supporting researchers in their quest for discovery through innovative biological products that fuel scientific advancement.
Please note that all services are for research use only. Not intended for any clinical use.
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