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TP53I11 Knockout Cell Lines

Gene: TP53I11

Official Full Name: tumor protein p53 inducible protein 11provided by HGNC

Gene Summary: Predicted to be involved in negative regulation of cell population proliferation. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33140 TP53I11 Knockout cell line (HeLa) Human TP53I11 1:3~1:6 Negative Online Inquiry
KO33141 TP53I11 Knockout cell line (HCT 116) Human TP53I11 1:2~1:4 Negative Online Inquiry
KO33142 TP53I11 Knockout cell line (HEK293) Human TP53I11 1:3~1:6 Negative Online Inquiry
KO33143 TP53I11 Knockout cell line (A549) Human TP53I11 1:3~1:4 Negative Online Inquiry

Background

TP53I11 Gene Knockout Cell Lines are genetically engineered cell models specifically designed to disrupt the TP53I11 gene, a critical regulator involved in various cellular processes, including apoptosis, DNA repair, and response to stress signals. These knockout cell lines serve as a powerful tool for researchers investigating the functional roles of TP53I11 in disease mechanisms, particularly in cancer, as well as in studies focused on cellular senescence and therapeutic resistance.

The primary function of these cell lines is to provide a controlled environment in which the absence of TP53I11 can be studied. Utilizing CRISPR-Cas9 technology, the knockout is achieved through precise edits in the genomic sequence, allowing scientists to elucidate the downstream effects of TP53I11 loss. Researchers can observe changes in cell proliferation, migration, and survival rates, enhancing our understanding of tumor biology and potential therapeutic pathways.

The scientific importance of TP53I11 Gene Knockout Cell Lines extends into multiple applications, including drug screening, biomarker discovery, and the development of targeted therapies. They offer unparalleled insight into the gene's involvement in pathophysiological processes, thus contributing significantly to translational medicine and the development of novel treatment strategies.

Compared to alternative cell models, the TP53I11 knockout lines present unique advantages, including specific genome editing techniques that ensure precise gene disruption with minimal off-target effects. This specificity is critical for delivering reliable and reproducible data that can enhance the credibility of research findings. Moreover, the availability of well-characterized cell lines accelerates experimental timelines, allowing for efficient validation of hypotheses.

This product is invaluable not only for researchers aiming to advance our understanding of TP53I11-related pathways but also for clinicians developing personalized therapies that target p53-associated tumor dynamics. The potential to improve patient outcomes through informed therapeutic strategies highlights the significance of integrating such advanced tools into both basic and applied research settings.

Our company is at the forefront of genomic innovation, committed to providing high-quality biological products that empower scientific discovery and drive advancements in health research. With a strong focus on precision and reliability, we ensure that our offerings, including TP53I11 Gene Knockout Cell Lines, meet the rigorous standards required by the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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