Gene: TOMM6
Official Full Name: translocase of outer mitochondrial membrane 6provided by HGNC
Gene Summary: Predicted to be involved in protein insertion into mitochondrial outer membrane. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20653 | TOMM6 Knockout cell line (HeLa) | Human | TOMM6 | 1:3~1:6 | Negative | Online Inquiry |
KO20654 | TOMM6 Knockout cell line (HCT 116) | Human | TOMM6 | 1:2~1:4 | Negative | Online Inquiry |
KO20655 | TOMM6 Knockout cell line (HEK293) | Human | TOMM6 | 1:3~1:6 | Negative | Online Inquiry |
KO20656 | TOMM6 Knockout cell line (A549) | Human | TOMM6 | 1:3~1:4 | Negative | Online Inquiry |
TOMM6 Gene Knockout Cell Lines are specialized cellular models designed to study the role and function of the translocase of the outer mitochondrial membrane 6 (TOMM6) gene. This gene is integral to mitochondrial dynamics and functionality, playing a critical role in protein import and mitochondrial biogenesis. The TOMM6 knockout models enable researchers to explore the cellular consequences of TOMM6 gene disruption, shedding light on mitochondrial dysfunctions linked to various diseases, including neurodegenerative disorders and metabolic syndromes.
The key function of TOMM6 Gene Knockout Cell Lines lies in their ability to exhibit alterations in mitochondrial morphology, dynamics, and apoptosis pathways, allowing for detailed mechanistic studies. The innovative CRISPR/Cas9 technology employed to create these cell lines ensures precise gene editing, leading to significant insights into the role of TOMM6 in maintaining cellular energy homeostasis and the implications of its dysregulation in disease.
The scientific importance of these cell lines is underscored by their applications in both research and clinical settings. They serve as invaluable tools for studying mitochondrial biology, drug screening, and the testing of therapeutic interventions targeting mitochondrial dysfunction. Researchers can utilize these knockout models to investigate the biochemical pathways that govern cell survival and death, providing a better understanding of the underlying mechanisms of diseases associated with mitochondrial impairment.
Compared to traditional knockout models, TOMM6 Gene Knockout Cell Lines offer enhanced specificity and reproducibility, minimizing off-target effects commonly seen with less precise methods. This advantage makes them a preferred option for scientists focused on high-precision research.
By utilizing TOMM6 Gene Knockout Cell Lines, researchers gain a unique opportunity to advance their knowledge of mitochondrial biology, helping to identify novel therapeutic targets and improve clinical outcomes. Our company prides itself on its expertise in developing innovative biological products tailored to meet the rigorous demands of contemporary research and clinical practice, ensuring that our products consistently support the scientific community in meaningful ways.
Please note that all services are for research use only. Not intended for any clinical use.
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