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TMEM74B Knockout Cell Lines

Gene: TMEM74B

Official Full Name: transmembrane protein 74Bprovided by HGNC

Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13292 TMEM74B Knockout cell line (HCT 116) Human TMEM74B 1:2~1:4 Negative Online Inquiry
KO13293 TMEM74B Knockout cell line (HEK293) Human TMEM74B 1:3~1:6 Negative Online Inquiry
KO13294 TMEM74B Knockout cell line (A549) Human TMEM74B 1:3~1:4 Negative Online Inquiry

Background

TMEM74B Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the expression of the TMEM74B gene, a critical component implicated in various cellular processes including immune responses and cellular signaling pathways. By utilizing advanced CRISPR/Cas9 genome editing technology, these knockouts provide a powerful tool for investigating the functional role of TMEM74B in both healthy and disease states.

The key mechanism of action involves the targeted disruption of the TMEM74B gene, leading to the abrogation of its protein product and enabling researchers to observe the phenotypic consequences of its loss. This allows for detailed studies into its involvement in cellular mechanisms, such as apoptosis, proliferation, and the modulation of immune responses, thus illuminating its potential roles in diseases like cancer and autoimmune disorders.

In research and clinical settings, TMEM74B Gene Knockout Cell Lines are invaluable. They serve as models for understanding the molecular underpinnings of diseases, facilitating drug discovery, and testing novel therapeutic approaches aimed at regulating immune function or combating malignancies. The availability of these cell lines supports the acceleration of discovery and validation processes in translational research.

One of the significant advantages of using TMEM74B Gene Knockout Cell Lines is their specificity and reliability compared to alternative models. Traditional methods, such as RNA interference, often result in incomplete gene knockdown and unpredictable off-target effects. In contrast, our knockout lines ensure full gene loss, providing cleaner data and more reproducible results.

Researchers, clinicians, and pharmaceutical companies will find TMEM74B Gene Knockout Cell Lines highly valuable for their applications in experimental and therapeutic contexts. They simplify the exploration of gene function and expedite the pathway toward new treatment paradigms.

Our company has decades of expertise in gene editing and cellular biology, providing an extensive range of high-quality biological products. Partnering with us means access to cutting-edge tools that significantly enhance the quality and efficacy of your research efforts.

Please note that all services are for research use only. Not intended for any clinical use.

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