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TMEM41A Knockout Cell Lines

Gene: TMEM41A

Official Full Name: transmembrane protein 41Aprovided by HGNC

Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23758 TMEM41A Knockout cell line (HeLa) Human TMEM41A 1:3~1:6 Negative Online Inquiry
KO23759 TMEM41A Knockout cell line (HCT 116) Human TMEM41A 1:2~1:4 Negative Online Inquiry
KO23760 TMEM41A Knockout cell line (HEK293) Human TMEM41A 1:3~1:6 Negative Online Inquiry
KO23761 TMEM41A Knockout cell line (A549) Human TMEM41A 1:3~1:4 Negative Online Inquiry

Background

TMEM41A Gene Knockout Cell Lines are specialized cell cultures engineered to lack the TMEM41A gene, which plays a crucial role in various cellular processes, including autophagy and endocytosis. These cell lines allow researchers to investigate the impact of TMEM41A on cellular behavior, leading to insights into its involvement in metabolic disorders and neurodegenerative diseases.

The primary mechanism of action involves the absence of the TMEM41A protein, which modulates lipid metabolism and mitochondrial function. By utilizing these knockout cell lines, scientists can discern how the loss of TMEM41A affects cellular pathways, contributing to a deeper understanding of pathophysiological conditions. This allows for novel candidate pathways and therapeutic targets to emerge, especially in the context of disease models that rely heavily on the regulation of autophagy.

Scientifically, TMEM41A Gene Knockout Cell Lines are vital tools in both research and clinical settings, providing a controlled environment for the study of gene function, cellular responses, and drug interactions. Their use can expedite the development of targeted therapies, particularly in oncology and neurobiology, where TMEM41A is implicated.

Compared to traditional wild-type cell lines, the TMEM41A knockout models offer unparalleled specificity in studying the gene's functional role, reducing the noise associated with interactions in non-targeted systems. Its unique selling points include the ability to conduct loss-of-function studies with accuracy, the inclusion of validated genetic modifications, and ease of use in experimental protocols.

For researchers and clinicians, these cell lines provide a crucial advantage in the quest to unlock new biological insights and therapeutic approaches. The precision and reliability of TMEM41A Gene Knockout Cell Lines present a valuable asset in both academic and pharmaceutical research contexts.

Our company prides itself on its leading expertise in cellular engineering and the provision of high-quality model systems to facilitate innovative research. We are committed to advancing scientific understanding through robust, reliable, and accessible biological products.

Please note that all services are for research use only. Not intended for any clinical use.

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