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TMEM39A Knockout Cell Lines

Gene: TMEM39A

Official Full Name: transmembrane protein 39Aprovided by HGNC

Gene Summary: Involved in negative regulation of autophagosome assembly; negative regulation of autophagosome maturation; and positive regulation of viral genome replication. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13328 TMEM39A Knockout cell line (HeLa) Human TMEM39A 1:3~1:6 Negative Online Inquiry
KO13329 TMEM39A Knockout cell line (HCT 116) Human TMEM39A 1:2~1:4 Negative Online Inquiry
KO13330 TMEM39A Knockout cell line (HEK293) Human TMEM39A 1:3~1:6 Negative Online Inquiry
KO13331 TMEM39A Knockout cell line (A549) Human TMEM39A 1:3~1:4 Negative Online Inquiry

Background

TMEM39A Gene Knockout Cell Lines are expertly engineered cellular models that enable researchers to study the biological implications of the TMEM39A gene in various contexts. TMEM39A encodes a transmembrane protein implicated in cellular processes such as endoplasmic reticulum function and protein homeostasis. The gene knockout technology utilized in producing these cell lines facilitates the complete ablation of TMEM39A expression, allowing for the detailed dissection of its role in cellular metabolism, signaling pathways, and disease mechanisms.

These cell lines function by providing a controlled environment in which the specific effects of TMEM39A deficiency can be analyzed. The knockout cells serve as a critical tool for elucidating the gene’s involvement in conditions such as neurodegenerative diseases and certain cancers. By comparing the knockout cell lines to their wild-type counterparts, researchers can identify phenotypic differences, assess alterations in biomolecular signaling, and facilitate the discovery of novel therapeutic targets.

The scientific importance of TMEM39A Gene Knockout Cell Lines lies in their capacity to drive key insights in both fundamental biology and translational research. Their application spans various fields, from drug screening and toxicological studies to the investigation of cellular stress responses and disease modeling. Compared to traditional cell lines, these knockout models provide a more precise tool for studying gene function, enabling researchers to obtain unambiguous data regarding the impact of TMEM39A on cellular homeostasis and pathology.

The primary advantages of TMEM39A Gene Knockout Cell Lines include their specificity, reproducibility, and the ability to study the loss-of-function effects of TMEM39A in a range of experimental setups. While other general knockout models exist, these cell lines are tailored to focus directly on TMEM39A, making them an essential resource for targeted research efforts.

For researchers and clinicians eager to unlock the mysteries surrounding TMEM39A, these cell lines offer invaluable insights that can inform both basic science and clinical strategies. This product represents our commitment to providing high-quality biological tools that empower research and innovation. Our company's expertise in cell line development ensures that TMEM39A Gene Knockout Cell Lines meet the rigorous standards necessary for robust scientific investigation and contribute significantly to advancements in precision medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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