Gene: TMEM182
Official Full Name: transmembrane protein 182provided by HGNC
Gene Summary: Predicted to be involved in myotube cell development involved in skeletal muscle regeneration; negative regulation of myoblast differentiation; and negative regulation of myoblast fusion. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26593 | TMEM182 Knockout cell line (HeLa) | Human | TMEM182 | 1:3~1:6 | Negative | Online Inquiry |
KO26594 | TMEM182 Knockout cell line (HCT 116) | Human | TMEM182 | 1:2~1:4 | Negative | Online Inquiry |
KO26595 | TMEM182 Knockout cell line (HEK293) | Human | TMEM182 | 1:3~1:6 | Negative | Online Inquiry |
KO26596 | TMEM182 Knockout cell line (A549) | Human | TMEM182 | 1:3~1:4 | Negative | Online Inquiry |
TMEM182 Gene Knockout Cell Lines are engineered cellular models that possess a complete disruption of the TMEM182 gene, a member of the transmembrane protein family. These cell lines serve as invaluable tools for researchers seeking to understand the biological functions of TMEM182 and its involvement in various physiological and pathological processes. The knockout mechanism is typically achieved through CRISPR/Cas9 technology, which allows for precise genome editing, resulting in the effective loss of function for this specific gene.
The primary function of TMEM182, believed to be associated with various cellular pathways, makes these knockout cell lines critical for studying the role of this gene in cellular mechanisms such as signaling, metabolism, and disease progression. By utilizing these cell lines, researchers can conduct detailed investigations into the effects of TMEM182 ablation on cellular behavior, gene expression, and response to therapeutic agents, enhancing our understanding of its potential implications in conditions like cancer, neurological disorders, and metabolic diseases.
In research and clinical settings, the scientific importance of TMEM182 Gene Knockout Cell Lines cannot be overstated. They provide a reliable platform for high-throughput screening, drug discovery, and target validation, thereby facilitating advancements in personalized medicine. Compared to alternative models, such as wild-type cell lines or less refined knockout systems, these specialized cell lines provide reproducibility and specificity, ensuring that experimental outcomes are directly attributable to TMEM182 modulation.
For researchers and clinicians, the value of these cell lines lies not only in their precision but also in their potential to uncover novel therapeutic targets and biomarkers. As the understanding of TMEM182's role in health and disease deepens, these knockout lines will be pivotal in translating research findings into clinical applications.
With our extensive expertise in cellular engineering and commitment to advancing biomedical research, we ensure that our TMEM182 Gene Knockout Cell Lines meet rigorous quality standards, empowering scientists to push the boundaries of knowledge and innovation in their fields.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.