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TMEM182 Knockout Cell Lines

Gene: TMEM182

Official Full Name: transmembrane protein 182provided by HGNC

Gene Summary: Predicted to be involved in myotube cell development involved in skeletal muscle regeneration; negative regulation of myoblast differentiation; and negative regulation of myoblast fusion. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26593 TMEM182 Knockout cell line (HeLa) Human TMEM182 1:3~1:6 Negative Online Inquiry
KO26594 TMEM182 Knockout cell line (HCT 116) Human TMEM182 1:2~1:4 Negative Online Inquiry
KO26595 TMEM182 Knockout cell line (HEK293) Human TMEM182 1:3~1:6 Negative Online Inquiry
KO26596 TMEM182 Knockout cell line (A549) Human TMEM182 1:3~1:4 Negative Online Inquiry

Background

TMEM182 Gene Knockout Cell Lines are engineered cellular models that possess a complete disruption of the TMEM182 gene, a member of the transmembrane protein family. These cell lines serve as invaluable tools for researchers seeking to understand the biological functions of TMEM182 and its involvement in various physiological and pathological processes. The knockout mechanism is typically achieved through CRISPR/Cas9 technology, which allows for precise genome editing, resulting in the effective loss of function for this specific gene.

The primary function of TMEM182, believed to be associated with various cellular pathways, makes these knockout cell lines critical for studying the role of this gene in cellular mechanisms such as signaling, metabolism, and disease progression. By utilizing these cell lines, researchers can conduct detailed investigations into the effects of TMEM182 ablation on cellular behavior, gene expression, and response to therapeutic agents, enhancing our understanding of its potential implications in conditions like cancer, neurological disorders, and metabolic diseases.

In research and clinical settings, the scientific importance of TMEM182 Gene Knockout Cell Lines cannot be overstated. They provide a reliable platform for high-throughput screening, drug discovery, and target validation, thereby facilitating advancements in personalized medicine. Compared to alternative models, such as wild-type cell lines or less refined knockout systems, these specialized cell lines provide reproducibility and specificity, ensuring that experimental outcomes are directly attributable to TMEM182 modulation.

For researchers and clinicians, the value of these cell lines lies not only in their precision but also in their potential to uncover novel therapeutic targets and biomarkers. As the understanding of TMEM182's role in health and disease deepens, these knockout lines will be pivotal in translating research findings into clinical applications.

With our extensive expertise in cellular engineering and commitment to advancing biomedical research, we ensure that our TMEM182 Gene Knockout Cell Lines meet rigorous quality standards, empowering scientists to push the boundaries of knowledge and innovation in their fields.

Please note that all services are for research use only. Not intended for any clinical use.

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