Gene: TMCO6
Official Full Name: transmembrane and coiled-coil domains 6provided by HGNC
Gene Summary: Predicted to enable nuclear import signal receptor activity. Predicted to be involved in protein import into nucleus. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13352 | TMCO6 Knockout cell line (HeLa) | Human | TMCO6 | 1:3~1:6 | Negative | Online Inquiry |
KO13353 | TMCO6 Knockout cell line (HCT 116) | Human | TMCO6 | 1:2~1:4 | Negative | Online Inquiry |
KO13354 | TMCO6 Knockout cell line (HEK293) | Human | TMCO6 | 1:3~1:6 | Negative | Online Inquiry |
KO13355 | TMCO6 Knockout cell line (A549) | Human | TMCO6 | 1:3~1:4 | Negative | Online Inquiry |
TMCO6 Gene Knockout Cell Lines are specifically engineered cell lines in which the TMCO6 gene has been inactivated, providing a powerful tool for studying the biological functions and pathways associated with this gene. The TMCO6 gene encodes a transmembrane protein believed to be involved in calcium signaling and cellular responses, making it a critical point of interest in neurobiology and cardiology research.
These knockout cell lines operate on the principle of gene editing, typically using CRISPR-Cas9 technology, which enables precise modification and elimination of the target TMCO6 gene. This mechanism allows researchers to observe the phenotypic and functional consequences of the loss of TMCO6, thus providing insights into its role in cellular processes. By using these specialized cell lines, scientists can delve deep into the implications of TMCO6 on cellular calcium homeostasis, apoptosis, and potential relationships with diseases, including neurodegenerative disorders and heart diseases.
The scientific importance of TMCO6 Gene Knockout Cell Lines lies in their ability to facilitate advanced studies that may lead to breakthroughs in understanding disease mechanisms or in developing targeted therapies. In clinical settings, such tools are invaluable for drug discovery and testing, as they allow for the creation of cellular models that mirror disease states relevant to TMCO6.
When compared to other genetic manipulation approaches, TMCO6 Gene Knockout Cell Lines offer several advantages: enhanced specificity due to targeted gene knockout, reproducibility in experiments, and a more straightforward approach to studying gene function without the complexity often associated with transient transfection methods.
For researchers and clinicians alike, the value of TMCO6 Gene Knockout Cell Lines is clear; they provide a clear path to unraveling complex biological questions, driving innovation in therapeutic interventions. Our company, with its extensive expertise in gene editing technologies and its commitment to advancing biological research, is proud to offer these specialized cell lines as part of our comprehensive product portfolio, catering specifically to the needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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