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TMCO1 Knockout Cell Lines

Gene: TMCO1

Official Full Name: transmembrane and coiled-coil domains 1provided by HGNC

Gene Summary: This locus encodes a transmembrane protein. Mutations at this locus have been associated with craniofacial dysmorphism, skeletal anomalies, and cognitive disability. Mutations at this locus have also been associated with open angle glaucoma blindness. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00116 TMCO1 Knockout cell line (293T) Human TMCO1 1:3~1:6 Negative Online Inquiry
KO21683 TMCO1 Knockout cell line (HeLa) Human TMCO1 1:3~1:6 Negative Online Inquiry
KO21684 TMCO1 Knockout cell line (HCT 116) Human TMCO1 1:2~1:4 Negative Online Inquiry
KO21685 TMCO1 Knockout cell line (HEK293) Human TMCO1 1:3~1:6 Negative Online Inquiry
KO21686 TMCO1 Knockout cell line (A549) Human TMCO1 1:3~1:4 Negative Online Inquiry

Background

TMCO1 Gene Knockout Cell Lines are specially engineered cell lines that have had the TMCO1 gene functionally disrupted or "knocked out." This advanced biotechnological tool allows researchers to investigate the biological roles of TMCO1 in various cellular processes and disease models, such as cancer and metabolic disorders. By removing the expression of this gene, scientists can study the resulting phenotypic changes and gain insight into TMCO1's contributions within the cell.

The key function of the TMCO1 Gene Knockout Cell Lines lies in their ability to serve as a model for elucidating the gene's specific mechanisms. TMCO1 is known to be involved in calcium homeostasis and lipid metabolism, thus providing an excellent system to explore these critical physiological processes. Through techniques such as Western blotting, RT-PCR, and confocal microscopy, researchers can evaluate the downstream effects resulting from the absence of TMCO1, allowing for comprehensive pathway analysis.

The scientific importance of these cell lines extends into both research and clinical settings. In the realm of academic research, they facilitate investigations into the gene's involvement in cellular and tissue responses, contributing to the understanding of various pathologies. Clinically, insights gained from these models could lead to the identification of novel therapeutic targets or biomarkers for diseases linked to TMCO1 dysregulation.

What sets TMCO1 Gene Knockout Cell Lines apart from alternative models is their reliability and specificity. Created using state-of-the-art CRISPR/Cas9 technology, they offer a high degree of precision and reproducibility, which is crucial for obtaining consistent results across experiments. This precision enables researchers to draw meaningful conclusions about TMCO1's role with greater confidence compared to more generalized gene silencing methods.

For researchers, clinicians, and biopharmaceutical companies, the ability to reliably manipulate genes and observe their effects is invaluable. The TMCO1 Gene Knockout Cell Lines not only deepen our understanding of cellular functions but also pave the way for innovative therapeutic strategies.

Our company specializes in cutting-edge genetic engineering and cell line development, ensuring that our products meet the highest standards of quality and efficacy. We are committed to advancing scientific discovery through our extensive portfolio of biological products, including the TMCO1 Gene Knockout Cell Lines.

Please note that all services are for research use only. Not intended for any clinical use.

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