Gene: TM4SF20
Official Full Name: transmembrane 4 L six family member 20provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the four-transmembrane L6 superfamily. Members of this family function in various cellular processes including cell proliferation, motility, and adhesion via their interactions with integrins. In human brain tissue, this gene is expressed at high levels in the parietal lobe, occipital lobe, hippocampus, pons, white matter, corpus callosum, and cerebellum. Knockout of the homologous gene in mouse results in a neurobehavioral phenotype with suggested enhanced motor coordination. A deletion mutation in the human gene is associated with specific language impairment-5. [provided by RefSeq, Jul 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13377 | TM4SF20 Knockout cell line (A549) | Human | TM4SF20 | 1:3~1:4 | Negative | Online Inquiry |
TM4SF20 Gene Knockout Cell Lines are specialized cellular models engineered to lack the TM4SF20 gene, which encodes a member of the transmembrane 4 superfamily involved in various cellular processes, including cell signaling and adhesion. These knockout cell lines are invaluable tools in biomedical research, particularly for studying the biological roles of TM4SF20 in various physiological and pathological contexts, such as cancer progression and immune responses.
The primary function of these knockout cell lines is to facilitate the exploration of the TM4SF20 gene's contributions to cellular mechanisms. By eliminating this gene's expression, researchers can investigate the resultant phenotypic changes, signaling pathways, and interaction networks that are influenced by TM4SF20. This targeted deletion allows for a clearer understanding of the gene's role in specific cellular functions, which is crucial for elucidating its contribution to diseases.
In scientific research, TM4SF20 Gene Knockout Cell Lines represent a significant advancement in the study of gene function, offering a precise way to dissect the capabilities and influences of the TM4SF20 gene in controlled environments. These models are particularly beneficial in preclinical studies aimed at developing therapeutic strategies targeting related pathways in various disease states.
The advantages of using our TM4SF20 Gene Knockout Cell Lines include their robust genetic validation, reproducibility, and the ability to generate consistent results across multiple laboratories. Unlike alternative models, our cell lines are meticulously characterized for off-target effects, ensuring that researchers obtain the highest fidelity data when investigating the role of TM4SF20. Furthermore, our cell lines are available with various backgrounds, allowing for tailored experimental designs that meet specific research needs.
Researchers and clinicians seeking to deepen their understanding of cellular mechanisms and disease processes will find tremendous value in our TM4SF20 Gene Knockout Cell Lines. With this product, users are not only equipped with a reliable experimental tool but also gain access to our extensive technical support and expertise. Our company is dedicated to providing high-quality biological products and cutting-edge solutions, ensuring that our customers can conduct their research with utmost confidence and precision.
Please note that all services are for research use only. Not intended for any clinical use.
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