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TM4SF18 Knockout Cell Lines

Gene: TM4SF18

Official Full Name: transmembrane 4 L six family member 18provided by HGNC

Gene Summary: Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30520 TM4SF18 Knockout cell line (HCT 116) Human TM4SF18 1:2~1:4 Negative Online Inquiry
KO30521 TM4SF18 Knockout cell line (A549) Human TM4SF18 1:3~1:4 Negative Online Inquiry

Background

TM4SF18 Gene Knockout Cell Lines are specifically developed cellular models that have been genetically engineered to lack the expression of the TM4SF18 (Transmembrane 4 Lsix3 Family Member 18) gene, a critical player in various cellular processes, including cell signaling, adhesion, and proliferation. These knockout cell lines serve as invaluable tools for researchers seeking to elucidate the physiological and pathological roles of TM4SF18 in diverse biological contexts.

The key function of TM4SF18 gene knockout cell lines lies in their ability to provide insights into gene function and regulatory mechanisms. By disrupting the TM4SF18 gene, these cell lines allow researchers to study the consequences of its absence on cellular behavior and interactions, thus enabling the dissection of signaling pathways and cell-matrix interactions that are vital for understanding processes such as tumorigenesis, metastasis, and immune response regulation.

The scientific importance of TM4SF18 gene knockout cell lines is underscored by their applications in both basic research and clinical settings. These models facilitate investigations into cancer biology, immune modulation, and developmental biology, offering researchers a platform to assess the impact of gene silencing on cellular responses, drug efficacy, and disease progression. They provide foundational data to help identify potential therapeutic targets for diseases where TM4SF18 has been implicated.

What distinguishes TM4SF18 gene knockout cell lines from alternative models is their specific focus on the TM4SF18 gene, enabling more nuanced studies compared to non-targeted or standard knockdown approaches. This specificity reduces background noise and enhances the reliability of experimental outcomes, providing more concrete evidence for hypotheses surrounding gene function.

For researchers and clinicians, the true value of these knockout cell lines lies in their robustness and the depth of analysis they facilitate. Investigating the implications of TM4SF18 removal can lead to breakthroughs in understanding complex diseases, improving the development of targeted therapeutic strategies.

Our company is committed to advancing scientific research by providing high-quality genetic models that drive innovation. With a dedication to precision and integrity in product offering, we empower the scientific community to achieve more in their quest for discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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