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THAP8 Knockout Cell Lines

Gene: THAP8

Official Full Name: THAP domain containing 8provided by HGNC

Gene Summary: Predicted to enable DNA binding activity and metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21292 THAP8 Knockout cell line (HeLa) Human THAP8 1:3~1:6 Negative Online Inquiry
KO21293 THAP8 Knockout cell line (HCT 116) Human THAP8 1:2~1:4 Negative Online Inquiry
KO21294 THAP8 Knockout cell line (HEK293) Human THAP8 1:3~1:6 Negative Online Inquiry
KO21295 THAP8 Knockout cell line (A549) Human THAP8 1:3~1:4 Negative Online Inquiry

Background

THAP8 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the THAP8 gene's functional role in various biological processes and disease mechanisms. Utilizing cutting-edge CRISPR-Cas9 genome editing technology, these cell lines provide a precise and effective means to create complete knockout phenotypes, enabling researchers to investigate the consequences of THAP8 absence on cellular behavior, signaling pathways, and gene expression profiles.

The key function of these knockout cell lines lies in their ability to eliminate the expression of the THAP8 gene, a known transcription factor implicated in diverse cellular functions and disorders, including neurodegenerative diseases and cancer. Researchers can utilize these cell lines to dissect the molecular pathways influenced by THAP8, advancing the understanding of its role in gene regulation, apoptosis, and cell cycle control. The precise knockout of THAP8 allows for robust functional analyses, shedding light on compensatory mechanisms and potential therapeutic targets.

The scientific importance of THAP8 Gene Knockout Cell Lines extends beyond basic research; they play a crucial role in preclinical studies and drug discovery. By providing insights into the gene's role in various diseases, these cell lines aid in the development of innovative treatment strategies. Moreover, as tools for high-throughput screening, they enable researchers to identify small molecules that can modulate THAP8-related pathways.

Compared to traditional gene knockdown methods, such as RNA interference, these knockout cell lines offer a more permanent and complete loss of gene function, reducing off-target effects and providing clearer insights into gene interactions. Additionally, the knockout approach allows for the study of THAP8 in different cellular contexts, enhancing the versatility of these models.

For researchers and clinicians dedicated to elucidating gene function and exploring novel therapeutic avenues, THAP8 Gene Knockout Cell Lines represent an invaluable resource. The ability to manipulate gene expression with precision facilitates meaningful discoveries in genetic research and therapeutic development.

As a leader in the production of cellular models, our company is committed to providing high-quality, reliable biological products that empower research and clinical innovation. With a deep understanding of genomic technologies, we deliver cutting-edge solutions that drive scientific advancement and improve health outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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