Gene: THADA
Official Full Name: THADA armadillo repeat containingprovided by HGNC
Gene Summary: This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13437 | THADA Knockout cell line (HeLa) | Human | THADA | 1:3~1:6 | Negative | Online Inquiry |
KO13438 | THADA Knockout cell line (HCT 116) | Human | THADA | 1:2~1:4 | Negative | Online Inquiry |
KO13439 | THADA Knockout cell line (HEK293) | Human | THADA | 1:3~1:6 | Negative | Online Inquiry |
KO13440 | THADA Knockout cell line (A549) | Human | THADA | 1:3~1:4 | Negative | Online Inquiry |
THADA Gene Knockout Cell Lines are specialized cellular models that have been genetically engineered to eliminate the expression of the THADA gene, a critical locus associated with metabolic regulation and various diseases, including obesity and diabetes. These knockout cell lines serve as valuable tools for researchers aiming to understand the role of THADA in cellular processes, gene expression, and pathological conditions.
The key function of THADA Gene Knockout Cell Lines lies in their ability to mimic loss-of-function scenarios for the THADA gene, allowing researchers to dissect the molecular mechanisms underlying gene expression, metabolic pathways, and cellular responses to stimuli. By studying these cell lines, scientists can elucidate the impact of THADA deficiency on cellular metabolism, signaling pathways, and overall cell function, ultimately bridging gaps in our understanding of its biological significance in disease contexts.
The scientific importance of these cell lines extends into both basic research and clinical applications. In research settings, they facilitate the investigation of genetic contributions to metabolic disorders, paving the way for targeted therapeutic strategies. Clinically, insights gained from these models can guide the development of novel interventions aimed at restoring normal metabolic functions or compensating for the loss of THADA-related activity.
THADA Gene Knockout Cell Lines offer distinct advantages over traditional models, including precise genomic alterations achieved through CRISPR/Cas9 technology, resulting in stable and reproducible gene knockout. Unlike conventional knockdown methodologies, these cell lines provide a permanent solution for gene loss studies, ensuring consistent results across experiments. Additionally, their availability in various cellular backgrounds enhances their versatility for a wide range of applications.
For researchers and clinicians targeting metabolic diseases, the value of THADA Gene Knockout Cell Lines is immense. By leveraging these cutting-edge models, users can gain profound insights into gene-function relationships, paving the way for innovative research and advancements in therapeutic strategies.
Our company is dedicated to providing high-quality, biologically relevant products tailored to the needs of researchers and clinicians, hence ensuring that our offerings, including the THADA Gene Knockout Cell Lines, meet the highest standards of scientific integrity and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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