Home / TGOLN2 Knockout Cell Lines

TGOLN2 Knockout Cell Lines

Gene: TGOLN2

Official Full Name: trans-golgi network protein 2provided by HGNC

Gene Summary: This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09743 TGOLN2 Knockout cell line (HeLa) Human TGOLN2 1:3~1:6 Negative Online Inquiry
KO09744 TGOLN2 Knockout cell line (HCT 116) Human TGOLN2 1:2~1:4 Negative Online Inquiry
KO09745 TGOLN2 Knockout cell line (HEK293) Human TGOLN2 1:3~1:6 Negative Online Inquiry
KO09746 TGOLN2 Knockout cell line (A549) Human TGOLN2 1:3~1:4 Negative Online Inquiry

Background

TGOLN2 Gene Knockout Cell Lines are specifically engineered cellular models designed to investigate the function and role of the TGOLN2 gene in various biological processes. These cell lines have undergone targeted gene editing to produce a complete knockout of the TGOLN2 gene, allowing researchers to study the gene's influence on cellular behavior and signaling pathways in a controlled environment. By eliminating the TGOLN2 gene, scientists can explore its contributions to critical pathways, including autophagy, protein trafficking, and cellular stress responses.

The mechanism behind the functionality of these knockout cell lines relies on CRISPR-Cas9 technology, a precise genome-editing tool that allows for the selective disruption of specific genes. This targeted approach enables researchers to observe the phenotypic and molecular changes associated with the loss of TGOLN2, thus providing invaluable insights into the gene's biological significance. As the role of TGOLN2 becomes elucidated, it may contribute to a better understanding of associated diseases, including cancer and neurodegenerative disorders.

The scientific importance of TGOLN2 Gene Knockout Cell Lines extends to various research applications, including drug discovery, genetic interaction studies, and the development of therapeutic interventions. Researchers can utilize these models to identify potential drug targets, explore gene-environment interactions, and assess the functional consequences of genetic alterations in vitro before translating findings to clinical settings.

What sets the TGOLN2 Gene Knockout Cell Lines apart from traditional cell lines or other knockout models is their specificity and verification through rigorous quality control measures, ensuring the reproducibility and reliability of experimental outcomes. These cell lines are invaluable tools for obtaining high-precision data and can accelerate the pace of discovery by allowing researchers to bypass the lengthy process of creating and validating their own knockout lines.

For researchers, clinicians, and institutions focusing on genetic research and therapeutic development, TGOLN2 Gene Knockout Cell Lines present a powerful resource that can drive innovation and contribute to breakthroughs in understanding complex biological systems. Backed by our company's extensive expertise in genetic engineering and cellular biology, our offerings reflect a commitment to advancing biological research and improving health outcomes through innovative scientific solutions.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.