Gene: TES
Official Full Name: testin LIM domain proteinprovided by HGNC
Gene Summary: Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a common fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq, Aug 2023]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28278 | TES Knockout cell line (HeLa) | Human | TES | 1:3~1:6 | Negative | Online Inquiry |
KO28279 | TES Knockout cell line (HCT 116) | Human | TES | 1:2~1:4 | Negative | Online Inquiry |
KO28280 | TES Knockout cell line (HEK293) | Human | TES | 1:3~1:6 | Negative | Online Inquiry |
KO28281 | TES Knockout cell line (A549) | Human | TES | 1:3~1:4 | Negative | Online Inquiry |
TES Gene Knockout Cell Lines are engineered cellular models that enable precise investigation of gene function by effectively eliminating the expression of target genes. Utilizing the latest CRISPR-Cas9 technology, these cell lines provide researchers with a platform to study gene-specific pathways and their implications in various biological processes. By creating specific genetic deletions, the TES Gene Knockout Cell Lines facilitate a robust understanding of gene roles in cellular behavior, including proliferation, differentiation, and response to external stimuli.
The key mechanism of action involves the targeted disruption of coding sequences, resulting in a frame-shift mutation or premature stop codons that prevent protein synthesis. This gene knockout approach allows for the systematic analysis of phenotypic changes, providing deeper insights into gene function and interaction networks. Researchers can utilize these cell lines to elucidate pathways relevant in areas such as cancer biology, neurobiology, immunology, and drug response – ultimately accelerating advancements in therapeutic development.
The scientific importance of these cell lines extends to both research and clinical applications, including the validation of new drug targets and the exploration of gene therapy interventions. Compared to traditional knockout approaches, TES Gene Knockout Cell Lines offer a higher degree of specificity, reduced off-target effects, and a faster turnaround time for experimental setups.
Distinct advantages of these cell lines include customization options for various genes of interest, along with comprehensive support from our scientific team for troubleshooting and experimental design, ensuring optimal results. By leveraging these advanced models, researchers and clinicians are equipped with a powerful tool to mitigate the challenges faced in studying gene function.
At our company, we pride ourselves on our commitment to innovation and excellence in the field of biological products. With extensive experience in genetic engineering and cell line development, we provide researchers with the quality and reliability necessary to push the boundaries of scientific inquiry. TES Gene Knockout Cell Lines represent not just a product, but a valuable asset in the quest for gene-related discoveries and advancements in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.