Gene: TEPSIN
Official Full Name: TEPSIN adaptor related protein complex 4 accessory proteinprovided by HGNC
Gene Summary: Located in coated vesicle membrane and trans-Golgi network membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23969 | TEPSIN Knockout cell line (HeLa) | Human | TEPSIN | 1:3~1:6 | Negative | Online Inquiry |
KO23970 | TEPSIN Knockout cell line (HCT 116) | Human | TEPSIN | 1:2~1:4 | Negative | Online Inquiry |
KO23971 | TEPSIN Knockout cell line (HEK293) | Human | TEPSIN | 1:3~1:6 | Negative | Online Inquiry |
KO23972 | TEPSIN Knockout cell line (A549) | Human | TEPSIN | 1:3~1:4 | Negative | Online Inquiry |
TEPSIN Gene Knockout Cell Lines are advanced, genetically modified cellular models specifically designed to study the function of the TEPSIN gene, crucial for various cellular processes, including protein sorting and trafficking. These cell lines are created using CRISPR/Cas9 technology, enabling precise and efficient disruption of the TEPSIN gene, allowing researchers to observe the resulting phenotypic changes and elucidate the gene's biological role.
The key mechanism underlying the functionality of TEPSIN Gene Knockout Cell Lines is the targeted deletion of the TEPSIN gene, which leads to altered intracellular signaling pathways and protein dynamics. As a result, researchers can investigate how the absence of TEPSIN impacts cellular behaviors such as proliferation, migration, and apoptosis. This molecular understanding has significant implications for diseases where TEPSIN dysregulation has been implicated, including certain cancers and neurodegenerative disorders.
The scientific importance of TEPSIN Gene Knockout Cell Lines is underscored by their broad applications in both basic and translational research. These cell lines serve as invaluable tools for understanding fundamental biological processes and can be leveraged in drug development and personalized medicine initiatives, providing insights into target validation and therapeutic strategies.
Compared to alternative cell models, such as overexpression or RNA interference systems, TEPSIN knockout lines offer a more authentic representation of the gene's functional loss, facilitating the study of loss-of-function phenotypes in a physiologically relevant context. Moreover, their adaptability to various assays, including high-throughput screening for drug discovery, enhances their utility in research endeavors.
For researchers and clinicians aiming to advance their understanding of TEPSIN-associated pathways or develop targeted therapies, TEPSIN Gene Knockout Cell Lines represent a compelling choice. Their reliability, alongside our commitment to quality and innovation in the field, positions our company as a trusted partner in cutting-edge biological research. Our extensive expertise in genetic engineering allows us to deliver products that empower scientists to unlock new discoveries and improve patient outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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