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TENT4B Knockout Cell Lines

Gene: TENT4B

Official Full Name: terminal nucleotidyltransferase 4Bprovided by HGNC

Gene Summary: Enables guanylyltransferase activity; poly(A) RNA polymerase activity; and telomerase RNA binding activity. Involved in RNA metabolic process; carbohydrate homeostasis; and regulation of nucleobase-containing compound metabolic process. Located in cytosol; nucleolus; and plasma membrane. Part of TRAMP complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13471 TENT4B Knockout cell line (HeLa) Human TENT4B 1:3~1:6 Negative Online Inquiry
KO13472 TENT4B Knockout cell line (HCT 116) Human TENT4B 1:2~1:4 Negative Online Inquiry
KO13473 TENT4B Knockout cell line (HEK293) Human TENT4B 1:3~1:6 Negative Online Inquiry
KO13474 TENT4B Knockout cell line (A549) Human TENT4B 1:3~1:4 Negative Online Inquiry

Background

TENT4B Gene Knockout Cell Lines are a specialized toolkit designed for cutting-edge cellular and molecular biology research, focusing on the study of gene function, protein interactions, and disease modeling. These cell lines are generated using advanced CRISPR/Cas9 technology, allowing for targeted disruption of the TENT4B gene, which is implicated in various biological processes including RNA metabolism and stress response. The knockout mechanism effectively removes the gene's expression, facilitating studies into the consequences of its absence at the cellular level.

The key functions of TENT4B Gene Knockout Cell Lines lie in their utility for functional genomics and drug discovery. Researchers can investigate the role of TENT4B in cellular contexts, such as proliferation, apoptosis, and differentiation, providing insights that can lead to the identification of novel therapeutic targets. Moreover, these knockout cell lines offer a platform for high-throughput screening of compounds that can restore normal function or modulate the pathway impacted by TENT4B deficiency.

The scientific importance of these cell lines is underscored by their applications in both research and clinical settings, including the elucidation of gene roles in cancer biology, neurodegenerative disorders, and metabolic syndromes. By offering a precise genetic tool, they empower researchers to generate robust in vitro models that closely mimic disease states, thereby accelerating the translational potential of their findings.

Compared to traditional methods of gene knockout, such as homologous recombination, TENT4B Gene Knockout Cell Lines represent a faster, more efficient alternative, significantly reducing the time and resources typically needed to achieve gene disruption. Additionally, the reliability and reproducibility of results obtained from these cell lines make them a valuable asset in research laboratories.

For researchers and clinicians alike, the investment in TENT4B Gene Knockout Cell Lines offers the advantage of streamlining experimental workflows while enhancing the quality of scientific inquiry. This product is essential for those aiming to make significant contributions to the understanding of gene function and its implications in health and disease.

With a strong foundation in molecular biology and gene editing technologies, our company is dedicated to providing high-quality biological products that meet the evolving needs of research communities, enabling innovation and discovery in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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