Gene: TCF19
Official Full Name: transcription factor 19provided by HGNC
Gene Summary: This gene encodes a protein that contains a PHD-type zinc finger domain and likely functions as a transcription factor. The encoded protein plays a role proliferation and apoptosis of pancreatic beta cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35082 | TCF19 Knockout cell line (HeLa) | Human | TCF19 | 1:3~1:6 | Negative | Online Inquiry |
KO35083 | TCF19 Knockout cell line (HCT 116) | Human | TCF19 | 1:2~1:4 | Negative | Online Inquiry |
KO35084 | TCF19 Knockout cell line (HEK293) | Human | TCF19 | 1:3~1:6 | Negative | Online Inquiry |
KO35085 | TCF19 Knockout cell line (A549) | Human | TCF19 | 1:3~1:4 | Negative | Online Inquiry |
The TCF19 Gene Knockout Cell Lines are engineered cellular models specifically designed to facilitate the study of TCF19 (T-cell factor 19), a transcription factor implicated in various biological processes, including cell proliferation and differentiation. Utilizing CRISPR-Cas9 gene-editing technology, these cell lines feature precise disruptions in the TCF19 gene, allowing researchers to explore the gene’s functional roles in cellular mechanisms and its impact on physiological and pathological states.
Functionally, TCF19 serves as a key regulator of gene expression, influencing pathways that are critical in development and immune responses. By providing a model with an inactivated TCF19 gene, researchers can study the consequent phenotypic changes in cellular behavior, gain insights into transcriptional regulation networks, and investigate potential compensatory mechanisms activated in its absence. This gene knockout system stands out as a robust tool for elucidating the complex roles of TCF19 in cancer biology, immunology, and stem cell research.
In terms of scientific importance, TCF19 Gene Knockout Cell Lines enable the discovery of novel drug targets, facilitate the understanding of disease mechanisms, and provide a platform for testing therapeutic interventions. Their applications span basic research to translational approaches, allowing scientists and clinicians to analyze how TCF19 dysfunction contributes to various diseases, including cancers and autoimmune disorders.
Key advantages of the TCF19 Gene Knockout Cell Lines include their high specificity and efficiency, achieved through advanced gene editing techniques, which provide results that are more reliable than traditional knockdown methods utilizing siRNA. Moreover, standardization across the cell lines minimizes variability, enhancing reproducibility in experiments.
For researchers and clinicians, the ability to dissect the impact of TCF19 on diverse cellular processes makes these cell lines not just valuable, but essential in advancing biomedical research. Our company prides itself on delivering high-quality, rigorously evaluated biological products that are backed by extensive expertise and a commitment to supporting the scientific community. By investing in TCF19 Gene Knockout Cell Lines, users can confidently embark on their research endeavors, pushing the boundaries of our understanding in molecular and cellular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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