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TBX20 Knockout Cell Lines

Gene: TBX20

Official Full Name: T-box transcription factor 20provided by HGNC

Gene Summary: This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13525 TBX20 Knockout cell line (HEK293) Human TBX20 1:3~1:6 Negative Online Inquiry
KO13526 TBX20 Knockout cell line (A549) Human TBX20 1:3~1:4 Negative Online Inquiry

Background

TBX20 Gene Knockout Cell Lines are a specialized research tool designed to investigate the functional roles of the TBX20 gene, a member of the T-box family of transcription factors crucial for cardiac development and function. These engineered cell lines provide researchers with a platform to study the consequences of TBX20 gene disruption on cellular processes and downstream signaling pathways.

The primary function of TBX20 involves the regulation of gene expression during heart development, influencing cardiomyocyte differentiation and proliferation. By utilizing CRISPR-Cas9 or other genomic editing techniques, these cell lines exhibit complete knockout of the TBX20 gene, enabling comprehensive analyses of gene function in both in vitro and in vivo contexts. The resulting phenotypic changes can shed light on cardiac-related pathologies, opening new avenues for understanding congenital heart defects and other cardiovascular diseases.

From a scientific perspective, TBX20 Gene Knockout Cell Lines are invaluable in both research and clinical settings. Their application extends to drug development and gene therapy, where exploring the therapeutic potential of TBX20 modulation can lead to innovative approaches for treating heart diseases. Furthermore, these cell lines contribute to regenerative medicine studies, providing insights into cardiac tissue engineering and repair.

One of the distinguishing advantages of our TBX20 Gene Knockout Cell Lines is their high specificity and efficiency in creating targeted gene disruptions, reducing off-target effects commonly associated with conventional methods. Compared to other gene editing technologies, our product is optimized for reproducibility, ensuring consistent and reliable results that are paramount for scientific research.

Researchers, clinicians, and biotechnologists will find value in our TBX20 Gene Knockout Cell Lines as they facilitate a deeper understanding of cardiac biology, ultimately contributing to advances in therapeutic interventions. Our company has a proven track record in providing high-quality biological products tailored for cutting-edge research, underscored by our commitment to scientific excellence and innovation in gene editing technologies.

Please note that all services are for research use only. Not intended for any clinical use.

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