Gene: TBX2
Official Full Name: T-box transcription factor 2provided by HGNC
Gene Summary: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35113 | TBX2 Knockout cell line (HEK293) | Human | TBX2 | 1:3~1:6 | Negative | Online Inquiry |
KO35114 | TBX2 Knockout cell line (A549) | Human | TBX2 | 1:3~1:4 | Negative | Online Inquiry |
TBX2 Gene Knockout Cell Lines are a specialized tool in molecular biology, designed to facilitate the comprehensive study of the TBX2 gene’s functions and its associated biological pathways. By employing CRISPR/Cas9 gene editing technology, these cell lines have had the TBX2 gene precisely inactivated, allowing researchers to explore the gene's role in immunological processes, cell adhesion, and developmental biology.
The primary function of TBX2 Gene Knockout Cell Lines is to permit the detailed examination of TBX2-related signaling pathways. TBX2 is a member of the T-box family of transcription factors that are crucial for diverse biological functions, including cell proliferation and differentiation. By utilizing these knockout cell lines, researchers can observe the phenotypic changes and functional consequences arising from the absence of TBX2, thereby gaining insights into its contribution to tumorigenesis and other diseases.
The scientific importance of these cell lines cannot be overstated. They are invaluable in both research and clinical settings for elucidating the mechanisms underlying TBX2-associated malignancies, advancing our understanding of developmental disorders, and screening potential therapeutic interventions. Researchers can utilize these knockout models for high-throughput screening of drug candidates, identifying specific pathways affected by TBX2 disruption, thus paving the way for targeted therapies.
Compared to traditional knockout models, our TBX2 Gene Knockout Cell Lines offer superior specificity and efficiency, minimizing off-target effects while maximizing ease of use. The cells are thoroughly characterized for their stability and reproducibility, ensuring consistent results across experiments.
For researchers and clinicians, adopting TBX2 Gene Knockout Cell Lines represents an investment in pioneering science and promising therapeutic development. The unique insights facilitated by these advanced cell lines contribute directly to cutting-edge research that can translate into real-world clinical applications.
As experts in biotechnology and genetic research, our company is dedicated to providing high-quality tools and resources that empower scientists to advance their work in genomics and therapeutic development. We pride ourselves on delivering reliable products that meet the rigorous demands of modern biological research.
Please note that all services are for research use only. Not intended for any clinical use.
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