Gene: TBC1D9B
Official Full Name: TBC1 domain family member 9Bprovided by HGNC
Gene Summary: Predicted to enable GTPase activator activity. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29940 | TBC1D9B Knockout cell line (HeLa) | Human | TBC1D9B | 1:3~1:6 | Negative | Online Inquiry |
KO29941 | TBC1D9B Knockout cell line (HCT 116) | Human | TBC1D9B | 1:2~1:4 | Negative | Online Inquiry |
KO29942 | TBC1D9B Knockout cell line (HEK293) | Human | TBC1D9B | 1:3~1:6 | Negative | Online Inquiry |
KO29943 | TBC1D9B Knockout cell line (A549) | Human | TBC1D9B | 1:3~1:4 | Negative | Online Inquiry |
TBC1D9B gene knockout cell lines are specialized cellular models engineered to lack the expression of the TBC1D9B gene, a critical component in cellular signaling pathways and cargo trafficking processes. These cells enable researchers to comprehensively investigate the functional role of TBC1D9B in various biological contexts, including the regulation of autophagy, cell proliferation, and responses to stress. The knockout is achieved through established gene-editing techniques like CRISPR/Cas9, ensuring precise alterations in the genomic sequence, facilitating the study of gene function and its implications in health and disease.
The key functions of TBC1D9B encompass its role in regulating endosomal trafficking and lysosomal function, which are vital for maintaining cellular homeostasis. By creating knockout models, scientists can elucidate the consequences of TBC1D9B deletion on intracellular transport, thereby advancing our understanding of related pathologies, including cancer and neurodegenerative diseases. This specific tool supports high-throughput screening and drug discovery efforts, allowing for the identification of potential therapeutic targets.
The importance of TBC1D9B gene knockout cell lines in scientific research cannot be overstated. They provide a clear advantage over wild-type cell lines by allowing researchers to delineate the gene's direct effects without confounding influences from its expression. This specificity makes it an indispensable tool for validating hypotheses related to gene function and disease mechanisms.
What sets our TBC1D9B knockout cell lines apart from alternatives is the rigorous validation and characterization they undergo. Each line is tested to confirm complete gene disruption and comprehensively analyzed for off-target effects, ensuring reliability and reproducibility. This commitment to quality and precision makes our product an exceptional choice for scientists who demand consistency and accuracy in their experiments.
By choosing TBC1D9B gene knockout cell lines, researchers and clinicians alike can enhance their understanding of fundamental biological processes and accelerate the translation of discoveries into clinical applications. Our company's expertise in genetic engineering and commitment to providing high-quality research tools means that you can trust our products to support your investigative needs with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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