Gene: Sat1
Official Full Name: spermidine/spermine N1-acetyl transferase 1provided by MGI
Gene Summary: Predicted to enable diamine N-acetyltransferase activity; identical protein binding activity; and spermidine binding activity. Acts upstream of or within regulation of cell population proliferation. Predicted to be located in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human SAT1 (spermidine/spermine N1-acetyltransferase 1). [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01249 | Sat1 Knockout cell line (RAW 264.7) | Mouse | Sat1 | Negative | Online Inquiry |
Sat1 Gene Knockout Cell Lines are specifically engineered cellular models that have undergone targeted gene editing to disrupt the expression of the Sat1 gene. This gene plays a crucial role in various biological processes, including cellular signaling, metabolic regulation, and response to environmental stimuli. By knocking out the Sat1 gene, these cell lines provide researchers with a powerful tool to study the functional consequences of gene loss and its implications in cellular behavior, differentiation, and disease mechanisms.
The key function of the Sat1 Gene Knockout Cell Lines lies in their ability to facilitate the elucidation of gene function through loss-of-function experiments. The mechanism behind their development involves advanced techniques such as CRISPR/Cas9 gene editing or RNA interference, which allow for precise modifications at the genomic level. These modifications not only enhance our understanding of the Sat1 gene's role in physiological and pathophysiological contexts but also enable the exploration of potential therapeutic targets for diseases linked to Sat1 dysregulation.
Scientifically, these cell lines are invaluable in a variety of research applications, including cancer biology, neurobiology, and metabolic disease studies. Understanding the biological pathways involving the Sat1 gene can lead to the identification of biomarkers and the development of novel therapeutic strategies. In the clinical setting, the insights gained from the use of these cell lines could potentially translate into personalized medicine approaches where therapeutic interventions are tailored based on the unique genetic makeup of patient-derived cells.
Distinctively, Sat1 Gene Knockout Cell Lines offer a consistent and reproducible system for researchers compared to traditional models that may exhibit genetic variability and unpredictability. Their highly specific gene knockout reduces background noise when measuring experimental outcomes, enabling more accurate data interpretation. Furthermore, these cell lines are also compatible with advanced screening technologies, such as high-throughput screening, making them an ideal choice for drug discovery and functional genomics studies.
For researchers and clinicians alike, the use of Sat1 Gene Knockout Cell Lines represents a strategic advantage in advancing scientific knowledge and developing innovative solutions to pressing biomedical challenges. With a commitment to quality and scientific rigor, our company specializes in providing top-tier biological products that empower researchers to achieve their goals efficiently and effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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