Gene: SYTL3
Official Full Name: synaptotagmin like 3provided by HGNC
Gene Summary: The protein encoded by this gene belongs to a family of peripheral membrane proteins that play a role in vesicular trafficking. This protein binds phospholipids in the presence of calcium ions. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22069 | SYTL3 Knockout cell line (HCT 116) | Human | SYTL3 | 1:2~1:4 | Negative | Online Inquiry |
KO22070 | SYTL3 Knockout cell line (A549) | Human | SYTL3 | 1:3~1:4 | Negative | Online Inquiry |
SYTL3 Gene Knockout Cell Lines are genetically modified cell lines created by targeted disruption of the SYTL3 gene, which encodes the syntaxin-binding protein implicated in intracellular vesicle transport. By utilizing the CRISPR-Cas9 gene-editing technology, these cell lines provide a powerful platform for the study of SYTL3’s role in cellular processes such as exocytosis, endocytosis, and synaptic communication. The knockout of SYTL3 creates a loss-of-function model that allows researchers to investigate the specific pathways and mechanisms that depend on this critical protein.
The primary function of SYTL3 Gene Knockout Cell Lines is to facilitate in-depth analyses of cellular dynamics, particularly how SYTL3 mutations or deletions affect vesicle trafficking, receptor recycling, and cytokine secretion. This is crucial for dissecting the molecular underpinnings of various biological phenomena, including neurodegenerative diseases and cancer, where SYTL3 is believed to play a significant role. In clinical settings, these cell lines can be pivotal for drug screening and the development of targeted therapies aimed at correcting or compensating for dysfunctional vesicle transport systems.
Compared to conventional wild-type cell lines, SYTL3 Gene Knockout Cell Lines offer distinct advantages, including specific insights into the consequences of SYTL3 loss in an in vitro environment, enhanced reproducibility of experiments, and the ability to model disease states more accurately. They provide researchers with a robust tool to dissect pathways affected by SYTL3 and explore potential therapeutic targets.
For researchers, clinicians, and biotechnologists, the ability to utilize SYTL3 knockout models can significantly enhance their understanding of vesicle-mediated processes, ultimately leading to breakthroughs in treatment strategies for diseases where these mechanisms are compromised. Our company is committed to providing high-quality biological products, and our expertise in gene-editing technology ensures that our SYTL3 Gene Knockout Cell Lines are rigorously validated, facilitating cutting-edge research and fostering innovation in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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