Gene: SYCP2
Official Full Name: synaptonemal complex protein 2provided by HGNC
Gene Summary: The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31904 | SYCP2 Knockout cell line (HeLa) | Human | SYCP2 | 1:3~1:6 | Negative | Online Inquiry |
KO31905 | SYCP2 Knockout cell line (A549) | Human | SYCP2 | 1:3~1:4 | Negative | Online Inquiry |
SYCP2 Gene Knockout Cell Lines are specialized cellular models designed for studying the role of the SYCP2 gene, which is crucial for proper meiosis and gametogenesis in eukaryotic organisms. These cell lines have been genetically modified to exhibit disruptions in the SYCP2 gene, enabling researchers to investigate the functional consequences of its absence on cell differentiation, chromosome pairing, and overall reproductive processes.
The key function of SYCP2 is to facilitate the assembly and stabilization of the synaptonemal complex during meiosis, thus ensuring accurate chromosome alignment and segregation. By utilizing our SYCP2 Gene Knockout Cell Lines, scientists can elucidate the mechanisms underlying meiotic failure, which is implicated in infertility and developmental disorders. The absence of SYCP2 allows for comparative analyses with wild-type cells, enabling a comprehensive understanding of the gene's role in meiotic progression and its potential impact on related pathologies.
The scientific importance of these cell lines extends beyond basic research; they have valuable applications in clinical settings. Researchers can utilize these models to screen for drugs that may restore normal meiotic function or to develop gene therapies targeting meiotic defects. Furthermore, understanding the implications of SYCP2 disruption could contribute to advancements in reproductive health, developmental biology, and genetic counseling.
What sets our SYCP2 Gene Knockout Cell Lines apart from alternative models is their derived specificity and reliability. These cell lines are generated using state-of-the-art CRISPR-Cas9 technology, ensuring precise gene editing and high reproducibility in experiments. This guarantees that the observed phenotypic effects are directly attributable to the SYCP2 gene knockout, bolstering the validity of research findings.
For researchers, clinicians, and biotechnologists invested in reproductive health and genetics, these cell lines provide an invaluable tool for pioneering innovative therapies and advancing our understanding of meiotic biology. Our company, recognized for its commitment to quality and scientific excellence, offers these SYCP2 Gene Knockout Cell Lines as part of a comprehensive product line designed to empower groundbreaking research and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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