Gene: STMND1
Official Full Name: stathmin domain containing 1provided by HGNC
Gene Summary: Predicted to enable tubulin binding activity. Predicted to be involved in microtubule depolymerization; neuron projection development; and regulation of microtubule polymerization or depolymerization. Predicted to be active in cytoplasm and neuron projection. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21367 | STMND1 Knockout cell line (HEK293) | Human | STMND1 | 1:3~1:6 | Negative | Online Inquiry |
STMND1 Gene Knockout Cell Lines are specifically engineered cell lines that have undergone a targeted deletion of the STMND1 gene, known for its role in the regulation of neuronal development and synaptic maintenance. By utilizing cutting-edge gene editing techniques, such as CRISPR/Cas9, these cell lines enable researchers to study the functional implications of STMND1 deficiency in a controlled environment.
The primary function of STMND1 is its involvement in the endosomal-lysosomal system, where it regulates the trafficking and degradation of synaptic proteins. By knocking out this gene, researchers can elucidate the downstream physiological effects, potentially contributing to a better understanding of neurodegenerative diseases and synaptic dysfunction. The mechanisms by which STMND1 influences cellular behavior involve modulation of signaling pathways that are critical for neuronal health and connectivity, making these knockout cell lines invaluable for elucidating complex neurobiological processes.
From a scientific perspective, STMND1 Gene Knockout Cell Lines serve as a robust tool for research into conditions such as Alzheimer's disease, Parkinson's disease, and other synaptic disorders. They facilitate high-throughput screening of therapeutic compounds and can support the development of novel treatments aimed at restoring synaptic function. Their unique ability to provide insights into STMND1-related pathologies offers advantages over traditional cell models, which may not accurately reflect the specific genetic and phenotypic characteristics relevant to these conditions.
By opting for our STMND1 Gene Knockout Cell Lines, researchers gain access to a versatile, reproducible, and validated model system that enhances the rigor and reproducibility of their studies. The precision of our gene editing process ensures that each cell line is consistently characterized, providing a reliable platform for experimental manipulation and assessment.
Our company specializes in developing high-quality, genetically modified cell lines with a commitment to advancing scientific research. By choosing STMND1 Gene Knockout Cell Lines, researchers and clinicians are equipped with a powerful resource that enriches their investigative and therapeutic approaches, ultimately paving the way for transformative breakthroughs in the understanding of neurological health.
Please note that all services are for research use only. Not intended for any clinical use.
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