Gene: STK25
Official Full Name: serine/threonine kinase 25provided by HGNC
Gene Summary: This gene encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18. Multiple alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31808 | STK25 Knockout cell line (HeLa) | Human | STK25 | 1:3~1:6 | Negative | Online Inquiry |
KO31809 | STK25 Knockout cell line (HCT 116) | Human | STK25 | 1:2~1:4 | Negative | Online Inquiry |
KO31810 | STK25 Knockout cell line (HEK293) | Human | STK25 | 1:3~1:6 | Negative | Online Inquiry |
KO31811 | STK25 Knockout cell line (A549) | Human | STK25 | 1:3~1:4 | Negative | Online Inquiry |
STK25 Gene Knockout Cell Lines are genetically modified cell lines that have been specifically engineered to lack the expression of the STK25 gene, which encodes a serine/threonine kinase involved in various cellular processes, including cell proliferation, apoptosis, and metabolism. These knockout models serve as powerful tools for elucidating the biological roles of STK25 in cellular signaling pathways and its implications in diseases such as cancer and metabolic disorders.
The key function of STK25 Gene Knockout Cell Lines lies in their ability to facilitate functional studies that assess the impact of STK25 absence on cellular behavior. By employing methods such as CRISPR-Cas9 gene editing, these cell lines provide a robust platform to investigate variations in cellular responses, including changes in growth rates, survival, and metabolic shifts. Researchers can utilize these knockout lines to dissect the mechanistic pathways regulated by STK25, enabling deeper insights into its contributions to disease pathology.
From a scientific perspective, these knockout lines are invaluable in both research and clinical settings. They offer significant advantages for drug testing and the development of therapeutic interventions targeting STK25-related pathways. Unlike standard cell lines, STK25 Gene Knockout Cell Lines provide a unique opportunity to observe phenotypic changes directly attributable to the absence of the STK25 gene, thereby enhancing the accuracy of research findings.
In comparison to alternative models, STK25 Gene Knockout Cell Lines stand out for their specific modulation of STK25 function, offering unparalleled specificity and reliability. This targeted approach allows researchers to minimize off-target effects commonly seen with broader gene suppression strategies, ultimately increasing the validity of experimental outcomes.
For researchers and clinicians committed to advancing the understanding of cellular mechanisms associated with STK25, these knockout cell lines represent an essential investment. Their precision enables innovative explorations into novel therapeutic avenues. Our company, dedicated to high-quality and reliable biological products, supports scientists in their quest for groundbreaking discoveries, ensuring they have access to the most sophisticated research tools available.
Please note that all services are for research use only. Not intended for any clinical use.
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