Gene: STAMBPL1
Official Full Name: STAM binding protein like 1provided by HGNC
Gene Summary: Enables K63-linked deubiquitinase activity. Involved in cellular response to L-leucine and positive regulation of TORC1 signaling. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20600 | STAMBPL1 Knockout cell line (HeLa) | Human | STAMBPL1 | 1:3~1:6 | Negative | Online Inquiry |
KO20601 | STAMBPL1 Knockout cell line (HCT 116) | Human | STAMBPL1 | 1:2~1:4 | Negative | Online Inquiry |
KO20602 | STAMBPL1 Knockout cell line (HEK293) | Human | STAMBPL1 | 1:3~1:6 | Negative | Online Inquiry |
KO20603 | STAMBPL1 Knockout cell line (A549) | Human | STAMBPL1 | 1:3~1:4 | Negative | Online Inquiry |
STAMBPL1 Gene Knockout Cell Lines are specialized cellular systems generated to facilitate the study of the STAMBPL1 gene, known for its role in cellular processes such as protein ubiquitination, cell signaling, and the modulation of inflammatory responses. By utilizing CRISPR-Cas9 gene-editing technology, these cell lines enable researchers to create precise knockouts of STAMBPL1, thereby unraveling its functions and interactions in various biological contexts.
The primary mechanism at work in STAMBPL1 knockout cell lines is the disruption of the STAMBPL1 gene. This leads to the absence of its product, which is pivotal in regulating the ubiquitin-proteasome pathway, a critical system for protein degradation. In performing functional assays, researchers can observe the downstream effects of STAMBPL1 deletion, contribute to the understanding of diseases such as cancer and autoimmune disorders, and explore potential therapeutic targets.
Scientifically, the ability to investigate STAMBPL1's role in biological pathways holds significant importance in both research and clinical settings. These cell lines are invaluable for drug discovery, allowing for high-throughput screening of compounds that might restore normal function in STAMBPL1-deficient cells. Additionally, understanding the gene's impact on disease mechanisms can aid in the development of novel therapies.
The STAMBPL1 Gene Knockout Cell Lines offer distinct advantages over traditional methods, such as knockout mice, which are time-consuming and expensive to develop. With these cell lines, researchers can rapidly obtain results, perform repeated experiments, and maintain consistent conditions across studies, thus enhancing reproducibility and efficiency.
For researchers, clinicians, and biopharmaceutical companies aiming to delve deeper into the implications of STAMBPL1 in health and disease, these cell lines represent a powerful tool for exploration and innovation. Our company specializes in developing high-quality biological products that meet the rigorous demands of modern research, ensuring that our customers have access to reliable and effective solutions for their studies.
Please note that all services are for research use only. Not intended for any clinical use.
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