Gene: STAM2
Official Full Name: signal transducing adaptor molecule 2provided by HGNC
Gene Summary: The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO11150 | STAM2 Knockout cell line (HeLa) | Human | STAM2 | 1:3~1:6 | Negative | Online Inquiry |
KO11151 | STAM2 Knockout cell line (HCT 116) | Human | STAM2 | 1:2~1:4 | Negative | Online Inquiry |
KO11152 | STAM2 Knockout cell line (HEK293) | Human | STAM2 | 1:3~1:6 | Negative | Online Inquiry |
KO11153 | STAM2 Knockout cell line (A549) | Human | STAM2 | 1:3~1:4 | Negative | Online Inquiry |
The STAM2 Gene Knockout Cell Lines represent a significant advancement in genetic research, providing scientists with a powerful tool for the study of STAM2 (Signal Transducing Adaptor Molecule 2) and its role in cellular signaling pathways. These engineered cell lines have undergone targeted gene disruption, effectively knocking out the STAM2 gene and allowing researchers to investigate the functional consequences of its absence. By employing CRISPR-Cas9 technology for precise genome editing, our STAM2 Gene Knockout Cell Lines enable detailed explorations of STAM2's involvement in biological processes such as endocytosis, inflammation, and insulin signaling.
In a clinical or research setting, the STAM2 Gene Knockout Cell Lines serve as invaluable resources for elucidating the underlying mechanisms of various diseases, particularly those associated with metabolic disorders and cancer. By studying these knockout models, researchers can perform phenotype assays that provide insight into how STAM2 influences cell growth, differentiation, and cellular responses to stimuli.
Compared to other available models, the STAM2 Gene Knockout Cell Lines showcase specific advantages such as consistent genetic modifications and reliable performance across experiments. They are optimized for high-throughput screening and can be utilized in diverse applications like drug discovery, gene therapy research, and biomarker identification. The ease of use, combined with comprehensive support for experimental design, makes these cell lines an exceptional choice for both novice and experienced researchers.
Investing in STAM2 Gene Knockout Cell Lines means equipping yourself with cutting-edge tools that enhance the understanding of complex biological systems. Our company specializes in developing high-quality biological products, ensuring that researchers have access to precisely engineered models that contribute significantly to the advancement of biomedical science.
Please note that all services are for research use only. Not intended for any clinical use.
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