Gene: ST6GALNAC2
Official Full Name: ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2provided by HGNC
Gene Summary: ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting (Samyn-Petit et al., 2000 [PubMed 10742600]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31678 | ST6GALNAC2 Knockout cell line (HeLa) | Human | ST6GALNAC2 | 1:3~1:6 | Negative | Online Inquiry |
KO31679 | ST6GALNAC2 Knockout cell line (HCT 116) | Human | ST6GALNAC2 | 1:2~1:4 | Negative | Online Inquiry |
ST6GALNAC2 Gene Knockout Cell Lines represent a pioneering advancement in genetic research, specifically designed to study the ST6GALNAC2 gene, which encodes for the enzyme responsible for synthesizing specific sialylated glycoproteins. These cell lines are meticulously engineered through CRISPR-Cas9 technology, resulting in a knockout of the ST6GALNAC2 gene, thereby providing researchers with a robust tool to investigate the implications of this gene in various biological processes, including cancer progression, immune response, and cell signaling pathways.
The primary function of these cell lines is to facilitate in-depth studies into the roles of sialylation in cellular behavior. By eliminating the ST6GALNAC2 gene, researchers can analyze the resultant physiological and molecular changes, thereby providing insights into the underlying mechanisms by which this gene influences disease states and therapeutic responses. The versatile applications of these knockout cell lines extend beyond basic research, encompassing preclinical assessments of drug efficacy and the investigation of potential therapeutic targets in oncology and immunology.
One of the distinctive advantages of our ST6GALNAC2 Gene Knockout Cell Lines lies in their high specificity and reproducibility compared to other genetic manipulation techniques, such as RNA interference or traditional gene editing tools. These knockout lines ensure complete and stable gene disruption, which significantly reduces off-target effects and enhances experimental clarity, making them indispensable for rigorous scientific inquiry.
For researchers and clinicians seeking reliable models for advanced genetic studies, our ST6GALNAC2 Gene Knockout Cell Lines provide unparalleled value. They empower scientists to unravel complex biological questions with precision and facilitate the development of new therapeutic strategies. Our company, with extensive expertise in cellular biology and genetic engineering, is committed to delivering high-quality biological products that support groundbreaking research and contribute to advancements in clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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