Gene: SRPK3
Official Full Name: SRSF protein kinase 3provided by HGNC
Gene Summary: This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28041 | SRPK3 Knockout cell line (HEK293) | Human | SRPK3 | 1:3~1:6 | Negative | Online Inquiry |
SRPK3 Gene Knockout Cell Lines are genetically engineered cell lines in which the SRPK3 gene has been inactivated or deleted, enabling researchers to study the specific biological functions and pathways associated with this serine/arginine-rich protein kinase. These cell lines facilitate the exploration of SRPK3's role in cellular processes, such as splicing regulation, signal transduction, and its involvement in various pathophysiological conditions, including cancer, neurodegenerative diseases, and cardiovascular disorders.
The primary function of the SRPK3 Gene Knockout Cell Lines stems from the elimination of SRPK3's kinase activity, which is crucial for the phosphorylation of splicing factors within the cell. This alteration allows for the dissection of SRPK3-mediated pathways and elucidates how its absence impacts alternative splicing, cell proliferation, and apoptosis. By providing a controlled experimental system, the knockout cell lines enable the identification of downstream molecular targets and the investigation of therapeutic interventions aimed at modulating SRPK3-related pathways.
In both research and clinical settings, SRPK3 Gene Knockout Cell Lines play a significant role in advancing knowledge regarding disease mechanisms and potential treatment targets. The ability to analyze the functional consequences of SRPK3 loss at the cellular level supports drug development initiatives, while simultaneously offering a platform for high-throughput screening of pharmacological compounds that could restore or alter the function of disrupted pathways.
Compared to conventional cell lines, SRPK3 Gene Knockout Cell Lines provide a unique advantage by offering a specific and targeted approach to investigate the functional implications of SRPK3 in various biological contexts. This specificity reduces background noise typically associated with using wild-type cell lines, allowing for clearer interpretations of experimental data. Moreover, these cell lines are readily accessible and compatible with existing laboratory protocols, streamlining the integration of SRPK3 research into broader experimental designs.
For researchers and clinicians focused on understanding the complex roles of SRPK3 in health and disease, our SRPK3 Gene Knockout Cell Lines represent a valuable resource that accelerates discovery and innovation. With a commitment to quality and precision, our company specializes in providing cutting-edge biological products that empower scientific advancements and support the pursuit of breakthroughs in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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