Gene: SRPK2
Official Full Name: SRSF protein kinase 2provided by HGNC
Gene Summary: Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in several processes, including R-loop processing; peptidyl-serine phosphorylation; and regulation of viral genome replication. Located in chromatin; cytosol; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35239 | SRPK2 Knockout cell line (HeLa) | Human | SRPK2 | 1:3~1:6 | Negative | Online Inquiry |
KO35240 | SRPK2 Knockout cell line (HCT 116) | Human | SRPK2 | 1:2~1:4 | Negative | Online Inquiry |
KO35241 | SRPK2 Knockout cell line (HEK293) | Human | SRPK2 | 1:3~1:6 | Negative | Online Inquiry |
KO35242 | SRPK2 Knockout cell line (A549) | Human | SRPK2 | 1:3~1:4 | Negative | Online Inquiry |
SRPK2 Gene Knockout Cell Lines are precisely engineered cellular models designed to silence the serine/arginine-rich protein kinase 2 (SRPK2) gene. This genetic modification allows researchers to investigate the functional role of SRPK2 in various biological processes, including RNA splicing, cellular signaling, and stress responses. By utilizing CRISPR/Cas9 technology, these knockout cell lines enable scientists to create a controlled environment to study phenotypic changes and molecular mechanisms associated with SRPK2 deficiency.
The primary function of SRPK2 is to regulate alternative splicing of pre-mRNAs, influencing gene expression profiles crucial for cellular functions. By knocking out the SRPK2 gene, researchers can assess the downstream effects on mRNA splicing events, identify target genes affected by SRPK2 activity, and elucidate pathways implicated in various diseases, notably cancer and neurodegenerative disorders. This makes SRPK2 Gene Knockout Cell Lines highly relevant in research aimed at understanding disease mechanisms and identifying potential therapeutic targets.
In comparison to conventional gene editing methods, our knockout cell lines offer unmatched specificity and efficiency, minimizing off-target effects and enabling rapid experimental workflows. Additionally, these cell lines can be easily maintained and are versatile for use in diverse experimental setups, from basic research to drug development.
For researchers and clinicians, the availability of SRPK2 Gene Knockout Cell Lines represents a valuable innovation, allowing for in-depth studies that can lead to breakthroughs in understanding complex diseases. With our commitment to delivering high-quality biological products backed by extensive expertise in molecular biology, we ensure that these cell lines meet rigorous standards for reliability and performance, empowering the scientific community to advance their research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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