Gene: SPOPL
Official Full Name: speckle type BTB/POZ protein likeprovided by HGNC
Gene Summary: Enables identical protein binding activity. Involved in negative regulation of protein ubiquitination and proteasome-mediated ubiquitin-dependent protein catabolic process. Part of Cul3-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13780 | SPOPL Knockout cell line (HeLa) | Human | SPOPL | 1:3~1:6 | Negative | Online Inquiry |
KO13781 | SPOPL Knockout cell line (HCT 116) | Human | SPOPL | 1:2~1:4 | Negative | Online Inquiry |
KO13782 | SPOPL Knockout cell line (HEK293) | Human | SPOPL | 1:3~1:6 | Negative | Online Inquiry |
KO13783 | SPOPL Knockout cell line (A549) | Human | SPOPL | 1:3~1:4 | Negative | Online Inquiry |
SPOPL Gene Knockout Cell Lines represent a cutting-edge product designed to facilitate genetic research by providing researchers with cells in which the SPOPL gene has been systematically disrupted. This revolutionary tool enables scientists to study the functional consequences of SPOPL deletion, particularly its role in cellular processes like protein degradation and gene expression regulation. Utilizing advanced CRISPR-Cas9 technology, these cell lines allow for precise gene editing, ensuring the absence of SPOPL functionality, thereby providing a reliable model for various studies.
The key function of SPOPL Gene Knockout Cell Lines lies in their ability to mimic human disease states or specific biological pathways. By eliminating the SPOPL gene, researchers can investigate its implications in cellular signaling, oncogenesis, and other physiological conditions, thereby advancing our understanding of related diseases. The accessibility of these cell lines streamlines experimentation, ensuring reproducibility and consistency across different assays, which is critical in both academic and clinical settings.
Scientifically, the importance of SPOPL knockout models lies in their potential application in drug discovery and development. By revealing the molecular mechanisms through which the SPOPL gene operates, researchers can better identify therapeutic targets for diseases involving aberrant SPOPL activity. Furthermore, these cell lines are invaluable in elucidating gene functional knockout impacts, enabling the assessment of compensatory molecular pathways.
What sets SPOPL Gene Knockout Cell Lines apart from alternative models is their specificity, along with the assurance of high-quality production and validation protocols that minimize the likelihood of off-target effects. Additionally, these lines are adaptable across multiple culture conditions and compatible with various assays, thus providing versatility in research approaches.
The value of these cell lines to researchers and clinicians cannot be overstated; they empower the scientific community to deepen their molecular insights and translate them into potential clinical applications. With a commitment to excellence and innovation, our company is dedicated to equipping scientists with robust tools that push the boundaries of genetic research, ensuring our offerings remain at the forefront of technological advancement in the biological sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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