Gene: SPIRE2
Official Full Name: spire type actin nucleation factor 2provided by HGNC
Gene Summary: Predicted to enable microtubule binding activity. Involved in establishment of meiotic spindle localization; formin-nucleated actin cable assembly; and positive regulation of double-strand break repair. Predicted to be located in cleavage furrow. Predicted to be active in cell cortex and cytoplasmic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24846 | SPIRE2 Knockout cell line (HeLa) | Human | SPIRE2 | 1:3~1:6 | Negative | Online Inquiry |
KO24847 | SPIRE2 Knockout cell line (HCT 116) | Human | SPIRE2 | 1:2~1:4 | Negative | Online Inquiry |
KO24848 | SPIRE2 Knockout cell line (HEK293) | Human | SPIRE2 | 1:3~1:6 | Negative | Online Inquiry |
KO24849 | SPIRE2 Knockout cell line (A549) | Human | SPIRE2 | 1:3~1:4 | Negative | Online Inquiry |
SPIRE2 Gene Knockout Cell Lines are a cutting-edge tool designed for precise genetic alteration, specifically engineered to facilitate the study of gene function and regulation in various cellular contexts. These cell lines are created using advanced CRISPR-Cas9 technology, enabling the targeted knockout of the SPIRE2 gene, which plays a crucial role in the regulation of cytoskeletal dynamics and cellular signaling. By disrupting the SPIRE2 gene, researchers can elucidate the biological pathways that are affected, allowing for deeper insight into cellular processes and potential disease mechanisms.
The primary function of SPIRE2 Gene Knockout Cell Lines involves their application in various experimental assays, including viability, proliferation, migration, and invasion studies. The mechanisms behind their utility lie in the gene's involvement in essential cellular functions; knocking out the SPIRE2 gene provides a clearer understanding of its role in oncogenic pathways and neurodegenerative diseases. This makes SPIRE2 lines invaluable for both basic research and translational studies, aiding the development of targeted therapeutics and personalized medicine approaches.
What sets SPIRE2 Gene Knockout Cell Lines apart from alternative products is their high specificity and efficiency in gene editing. With minimal off-target effects and validated knockout efficiency, researchers can achieve reliable results, reducing the time and resources typically required for genetic studies. Additionally, these cell lines come with robust and easy-to-use protocols, streamlining the adoption process for both novice and experienced scientists.
For researchers and clinicians aiming to unravel gene function and explore therapeutic innovations, SPIRE2 Gene Knockout Cell Lines represent a potent resource, facilitating discoveries that could lead to the advancement of molecular medicine. Our company prides itself on delivering rigorously validated biological products, backed by a team of experts in genetic engineering and molecular biology, ensuring that our offerings not only meet but exceed the expectations of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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