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SPECC1L Knockout Cell Lines

Gene: SPECC1L

Official Full Name: sperm antigen with calponin homology and coiled-coil domains 1 likeprovided by HGNC

Gene Summary: This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29345 SPECC1L Knockout cell line (HeLa) Human SPECC1L 1:3~1:6 Negative Online Inquiry
KO29346 SPECC1L Knockout cell line (HCT 116) Human SPECC1L 1:2~1:4 Negative Online Inquiry
KO29347 SPECC1L Knockout cell line (HEK293) Human SPECC1L 1:3~1:6 Negative Online Inquiry
KO29348 SPECC1L Knockout cell line (A549) Human SPECC1L 1:3~1:4 Negative Online Inquiry

Background

SPECC1L Gene Knockout Cell Lines are a state-of-the-art biological tool designed for the detailed study of the SPECC1L gene and its associated functions in various cellular processes. These cell lines have been constructed using advanced CRISPR-Cas9 gene editing technology to achieve precise gene disruption, allowing researchers to investigate the resulting phenotypic changes. The genetic knockout of SPECC1L facilitates the exploration of its role in cellular mechanisms such as cytoskeletal organization, cell migration, and tissue morphogenesis.

The key function of the SPECC1L Gene Knockout Cell Lines lies in their ability to serve as a vital resource for elucidating gene function in both fundamental and applied biological research. By effectively silencing the SPECC1L gene, researchers can observe alterations in cellular behavior and signaling pathways, providing insights into neoplasia, developmental biology, and various disease states, particularly in cancer research where the gene's implications are being actively examined.

The scientific importance of these cell lines extends to their application in drug discovery and therapeutic development, as they offer a reliable model for testing potential interventions targeting SPECC1L-related pathways. Compared to alternative cell line models, which may exhibit variable genetic backgrounds, the SPECC1L gene knockout lines provide a standardized approach, enabling reproducibility and consistency in experimental outcomes.

One of the primary advantages of using SPECC1L Gene Knockout Cell Lines is their capacity to accelerate the understanding of gene function without the variability associated with traditional knockdown techniques, such as siRNA treatment. This precision allows for a more accurate assessment of gene involvement in specific cellular processes. Additionally, the ease of use and adaptability of these cell lines in various experimental setups further enhances their appeal to researchers across diverse fields.

The value of SPECC1L Gene Knockout Cell Lines is evident for researchers and clinicians pursuing an understanding of genetic contributions to health and disease. By leveraging these cutting-edge cell lines, users can gain unparalleled insights that could lead to novel therapeutic strategies and innovations in clinical applications.

Our company prides itself on its commitment to delivering high-quality, scientifically validated biological products that empower researchers and healthcare professionals. With rigorous quality control and a passion for advancing scientific knowledge, we stand at the forefront of biological research solutions.

Please note that all services are for research use only. Not intended for any clinical use.

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