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SPATA7 Knockout Cell Lines

Gene: SPATA7

Official Full Name: spermatogenesis associated 7provided by HGNC

Gene Summary: This gene, originally isolated from testis, is also expressed in retina. Mutations in this gene are associated with Leber congenital amaurosis and juvenile retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13817 SPATA7 Knockout cell line (HeLa) Human SPATA7 1:3~1:6 Negative Online Inquiry
KO13818 SPATA7 Knockout cell line (HCT 116) Human SPATA7 1:2~1:4 Negative Online Inquiry
KO13819 SPATA7 Knockout cell line (HEK293) Human SPATA7 1:3~1:6 Negative Online Inquiry
KO13820 SPATA7 Knockout cell line (A549) Human SPATA7 1:3~1:4 Negative Online Inquiry

Background

SPATA7 Gene Knockout Cell Lines represent a pivotal advancement in the realm of genetic research, providing researchers with invaluable tools for studying the role of the SPATA7 gene in various biological processes. These engineered cell lines are created through CRISPR/Cas9 technology, resulting in targeted deletions of the SPATA7 gene, allowing for precise analysis of its functions, interactions, and contributions to cellular pathways.

The SPATA7 gene is implicated in important biological functions, including photoreceptor development and synaptic transmission in the retina. By utilizing these knockout cell lines, scientists can elucidate the role of SPATA7 in disease models, especially those related to retinal degeneration, paving the way for novel therapeutic strategies. The mechanisms of action include disrupting normal protein interactions and cellular signaling pathways that involve SPATA7, thus enabling researchers to dissect the molecular underpinnings of related disorders.

The scientific significance of SPATA7 Gene Knockout Cell Lines extends to both basic and applied research settings. Researchers can utilize these cell lines to explore gene function, validate drug targets, and develop gene therapies. In clinical contexts, understanding the functionalities of SPATA7 may contribute greatly to advancing personalized medicine for patients with vision disorders linked to mutations in this gene.

One of the distinct advantages of our SPATA7 Gene Knockout Cell Lines lies in their high specificity and reliability, achieved through rigorous validation processes. Unlike alternative models, these cell lines offer a consistent platform for experimental reproducibility and lower off-target effects, thereby enhancing the integrity of scientific findings. Furthermore, they are readily available and easy to use, facilitating seamless integration into existing research workflows.

For researchers and clinicians focused on genetic and cellular biology, the SPATA7 Gene Knockout Cell Lines are an indispensable resource for accelerating discovery and understanding gene function in health and disease. Our extensive expertise in advancing biological products ensures that these cell lines are produced under stringent quality control measures, ultimately supporting our commitment to providing exceptional research tools that empower scientific innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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