Gene: SPATA2
Official Full Name: spermatogenesis associated 2provided by HGNC
Gene Summary: Enables signaling receptor complex adaptor activity and ubiquitin-specific protease binding activity. Involved in several processes, including protein deubiquitination; regulation of necroptotic process; and regulation of tumor necrosis factor-mediated signaling pathway. Located in cytoplasm; fibrillar center; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32708 | SPATA2 Knockout cell line (HeLa) | Human | SPATA2 | 1:3~1:6 | Negative | Online Inquiry |
KO32709 | SPATA2 Knockout cell line (HCT 116) | Human | SPATA2 | 1:2~1:4 | Negative | Online Inquiry |
KO32710 | SPATA2 Knockout cell line (HEK293) | Human | SPATA2 | 1:3~1:6 | Negative | Online Inquiry |
KO32711 | SPATA2 Knockout cell line (A549) | Human | SPATA2 | 1:3~1:4 | Negative | Online Inquiry |
SPATA2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the SPATA2 gene, allowing researchers to study the gene's function and associated biological pathways. SPATA2 is implicated in various cellular processes, including spermatogenesis and potential tumorigenesis, making these knockout models invaluable for functional genomics and cancer research.
These cell lines enable the precise examination of gene function through loss-of-function analyses. By comparing the phenotypic and molecular characteristics of SPATA2-deficient cells to wild-type counterparts, researchers can dissect the role of SPATA2 in cellular signaling, differentiation, and disease development. The mechanisms involved often relate to the regulation of gene expression and cellular stress responses, contributing to our understanding of reproductive biology and malignancies.
The scientific importance of SPATA2 Gene Knockout Cell Lines extends to their profound applications in both research and clinical settings. These models serve as crucial tools for elucidating the pathophysiology of diseases linked to SPATA2 abnormalities and can facilitate the discovery of potential therapeutic targets. They can also be used in drug screening platforms, helping identify compounds that may modulate the effects of SPATA2 loss.
What sets SPATA2 Gene Knockout Cell Lines apart from traditional cell models is their specificity and reliability. Unlike other genetic modification techniques that may result in off-target effects, these knockout lines provide a clean genetic background for the study of SPATA2 functions, ensuring the validity of experimental results. Additionally, their standardized protocols for generation and maintenance enhance reproducibility across different laboratories.
For researchers and clinicians, the value of SPATA2 Gene Knockout Cell Lines lies in their capability to offer insights into complex biological processes and their direct applications in therapeutic advancements. With our company’s expertise in cellular biology and genomic technologies, we are committed to supporting scientific discovery through high-quality, reliable models tailored for your research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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