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SP9 Knockout Cell Lines

Gene: SP9

Official Full Name: Sp9 transcription factorprovided by HGNC

Gene Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13844 SP9 Knockout cell line (HEK293) Human SP9 1:3~1:6 Negative Online Inquiry
KO13845 SP9 Knockout cell line (A549) Human SP9 1:3~1:4 Negative Online Inquiry

Background

SP9 Gene Knockout Cell Lines are expertly developed cellular models that have undergone precise genetic modifications to inactivate the SP9 gene, allowing for the study of its biological functions and interactions in various cellular contexts. These cell lines are essential in dissecting the role of SP9, a transcription factor involved in neurogenesis, with critical implications in developmental biology and oncogenesis.

The key mechanism by which SP9 Gene Knockout Cell Lines operate is through the targeted deletion of the SP9 gene using advanced genome-editing techniques such as CRISPR-Cas9. This knockout leads to a loss of function that enables researchers to observe phenotypic changes, signaling pathway alterations, and gene expression profile modifications that are otherwise masked in wild-type cells. By systematically analyzing these changes, scientists can gain insight into the causal relationships between SP9 expression and various physiological and pathological conditions.

In a research setting, these cell lines serve as pivotal tools for understanding the molecular mechanisms underlying diseases, particularly those involving neural differentiation and tumor biology. Their application extends into pharmacological studies, where researchers can evaluate the effects of potential therapeutic agents on SP9-mediated pathways. Clinically, this understanding could pave the way for novel treatment strategies in neurodevelopmental disorders and cancers.

SP9 Gene Knockout Cell Lines offer several advantages over traditional models. Unlike transient knockdown methods, our stable cell lines ensure consistent genetic modification, enabling more reliable replication of experiments. Moreover, the availability of these specialized cell lines reduces time and resource investments when establishing experimental setups, providing scientists with immediate access to in-depth studies on SP9 without requiring extensive gene-editing experience.

This product is invaluable for researchers and clinicians looking to advance their understanding of complex biological processes and therapeutic targets. With a reliable tool for exploring gene functionality, users will have the resources necessary to make significant discoveries and clinical advancements.

Our company brings years of expertise in gene editing technology and cellular model development, ensuring that every SP9 Gene Knockout Cell Line meets rigorous scientific standards for quality and functionality. By choosing our products, researchers align with a partner dedicated to accelerating innovation in biological research and therapy.

Please note that all services are for research use only. Not intended for any clinical use.

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