Gene: SP6
Official Full Name: Sp6 transcription factorprovided by HGNC
Gene Summary: SP6 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26019 | SP6 Knockout cell line (HeLa) | Human | SP6 | 1:3~1:6 | Negative | Online Inquiry |
KO26020 | SP6 Knockout cell line (HCT 116) | Human | SP6 | 1:2~1:4 | Negative | Online Inquiry |
KO26021 | SP6 Knockout cell line (HEK293) | Human | SP6 | 1:3~1:6 | Negative | Online Inquiry |
KO26022 | SP6 Knockout cell line (A549) | Human | SP6 | 1:3~1:4 | Negative | Online Inquiry |
SP6 Gene Knockout Cell Lines are genetically modified cell lines that have been engineered to disrupt the expression of specific target genes, facilitating in-depth functional studies of gene function and regulation. Utilizing the advanced CRISPR-Cas9 technology, these cell lines provide a powerful platform for researchers to investigate the role of individual genes in cellular processes, disease states, and therapeutic responses.
The key mechanism behind the functionality of SP6 Gene Knockout Cell Lines lies in their precision gene editing capabilities. By targeting specific sequences within the genome, the CRISPR system introduces double-strand breaks, leading to error-prone repair mechanisms that result in frameshifts or deletions. This results in a complete loss of gene function, thereby permitting the elucidation of gene interactions and the study of phenotypic outcomes resulting from gene inactivation.
The scientific importance of SP6 Gene Knockout Cell Lines cannot be overstated. In research settings, they serve as invaluable tools for the dissection of signaling pathways, exploration of genetic interactions, and development of disease models, contributing significantly to our understanding of cellular mechanisms. Clinically, these cell lines pave the way for novel therapeutic strategies by identifying potential drug targets and elucidating resistance mechanisms in various diseases, including cancer and genetic disorders.
Compared to traditional gene knockout methods, the SP6 Gene Knockout Cell Lines offer unparalleled specificity and efficiency. They provide consistent, reliable results and reduce variability that is often seen with other approaches. Additionally, these cell lines are available in multiple backgrounds, tailored for diverse experimental setups, thereby enhancing their utility across different research disciplines.
For researchers and clinicians alike, the SP6 Gene Knockout Cell Lines deliver a significant advantage in both speed and accuracy, facilitating groundbreaking discoveries that advance our understanding of biology and enhance therapeutic innovation. With a commitment to cutting-edge technology and a portfolio of biologically relevant products, our company positions itself at the forefront of genomic research, ensuring that our offerings meet the evolving needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.