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SNX7 Knockout Cell Lines

Gene: SNX7

Official Full Name: sorting nexin 7provided by HGNC

Gene Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region like some family members, and its exact function is unknown. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Jun 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22598 SNX7 Knockout cell line (HeLa) Human SNX7 1:3~1:6 Negative Online Inquiry
KO22599 SNX7 Knockout cell line (HCT 116) Human SNX7 1:2~1:4 Negative Online Inquiry
KO22600 SNX7 Knockout cell line (HEK293) Human SNX7 1:3~1:6 Negative Online Inquiry
KO22601 SNX7 Knockout cell line (A549) Human SNX7 1:3~1:4 Negative Online Inquiry

Background

SNX7 Gene Knockout Cell Lines are genetically modified cell lines characterized by the targeted disruption of the SNX7 gene, which encodes a protein involved in the sorting and trafficking of membrane proteins within cells. This innovative product enables researchers to study the functional consequences of SNX7 deficiency, thereby elucidating its role in various cellular processes, including endocytosis, exocytosis, and signal transduction pathways. The knockout mechanism allows for the precise observation of changes in cellular behavior and phenotype, providing vital insights into cellular dynamics and disease mechanisms.

The primary function of SNX7 Gene Knockout Cell Lines is to facilitate investigations into how the absence of SNX7 affects cellular processes and interactions. The gene product, SNX7, is implicated in the assembly of protein complexes that regulate the recycling and degradation of membrane proteins. Through the knockout model, researchers can analyze alterations in protein localization, turnover, and associated signaling events, laying the groundwork for a better understanding of its contributions to various biological phenomena.

In the context of scientific research and clinical applications, these knockout cell lines offer considerable value. They serve as a robust tool for dissecting the molecular underpinnings of diseases such as cancer and neurodegenerative disorders, where dysregulation of protein trafficking can play a pivotal role. By using these cell lines, researchers can explore novel therapeutic targets and pathways, accelerating preclinical studies and drug discovery initiatives.

Compared to alternative models, SNX7 Gene Knockout Cell Lines provide a unique advantage by enabling researchers to observe the direct effects of complete gene loss on cellular function, which is often more revealing than partial inhibition or pharmacological modulation of related pathways. Furthermore, these cell lines come validated for consistent performance, allowing for reproducible results across studies.

The value of our SNX7 Gene Knockout Cell Lines extends beyond their immediate applications; they represent a powerful resource for researchers and clinicians eager to advance their understanding of cellular mechanisms and disease pathogenesis. Our company prides itself on its dedication to producing high-quality biological products backed by expertise in molecular biology and genetics, ensuring that our customers have access to the tools they need to drive their research forward.

Please note that all services are for research use only. Not intended for any clinical use.

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