Home / SNX12 Knockout Cell Lines

SNX12 Knockout Cell Lines

Gene: SNX12

Official Full Name: sorting nexin 12provided by HGNC

Gene Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. A similar protein in mouse may be involved in regulating the neurite outgrowth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03226 SNX12 Knockout cell line (HeLa) Human SNX12 1:3~1:6 Negative Online Inquiry
KO03227 SNX12 Knockout cell line (HCT 116) Human SNX12 1:2~1:4 Negative Online Inquiry
KO03228 SNX12 Knockout cell line (HEK293) Human SNX12 1:3~1:6 Negative Online Inquiry
KO03229 SNX12 Knockout cell line (A549) Human SNX12 1:3~1:4 Negative Online Inquiry

Background

SNX12 Gene Knockout Cell Lines are genetically engineered cell lines that have had the SNX12 gene deliberately disrupted or "knocked out," allowing researchers to study the functional consequences of SNX12 loss. SNX12 is a member of the sorting nexin family, which is known to be involved in endosomal trafficking and cellular signaling processes. By utilizing these knockout cell lines, scientists can investigate the role of SNX12 in various cellular mechanisms, including endocytosis, protein sorting, and signal transduction, providing valuable insights into its biological functions.

The primary mechanism by which the SNX12 Gene Knockout Cell Lines operate revolves around the complete absence of SNX12 protein expression, which facilitates a clearer understanding of its physiological roles in cellular contexts. Researchers can observe the effects of SNX12 deficiency on cellular morphology, trafficking pathways, and overall cellular homeostasis. This approach is particularly significant in the context of investigations into diseases where SNX12 may play a pivotal role, enabling the identification of potential therapeutic targets.

In terms of scientific importance, these knockout cell lines have implications in research areas such as cancer biology, neurological disorders, and metabolic diseases. Researchers can utilize these models to explore disease mechanisms and test drug candidates in a controlled environment, thereby accelerating the path from discovery to clinical application. Compared to conventional overexpression models or wild-type cell lines, SNX12 Gene Knockout Cell Lines provide a more precise and relevant framework for examining gene function.

The distinct advantage of using SNX12 Gene Knockout Cell Lines lies in their ability to simulate pathophysiological conditions resulting from the loss of SNX12 function more accurately than alternatives. This specificity empowers researchers to delineate the consequences of gene disruption with greater clarity and reliability.

For researchers, clinicians, and pharmaceutical developers, the value of SNX12 Gene Knockout Cell Lines is evident: they are essential tools for elucidating the complexities of cellular behavior related to SNX12, paving the way for novel discoveries and therapeutic strategies. Our company specializes in providing high-quality biological products tailored to meet the diverse needs of the scientific community, backed by rigorous validation and expertise in genetic engineering.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.