Gene: SNAI3
Official Full Name: snail family transcriptional repressor 3provided by HGNC
Gene Summary: SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis (Katoh and Katoh, 2003 [PubMed 12579345]).[supplied by OMIM, Apr 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13882 | SNAI3 Knockout cell line (HCT 116) | Human | SNAI3 | 1:2~1:4 | Negative | Online Inquiry |
KO13883 | SNAI3 Knockout cell line (HEK293) | Human | SNAI3 | 1:3~1:6 | Negative | Online Inquiry |
SNAI3 Gene Knockout Cell Lines are genetically engineered cell lines in which the SNAI3 (Snail Family Transcriptional Repressor 3) gene has been completely disrupted. This product serves as an essential tool for researchers seeking to study the biological functions of SNAI3 in various cellular contexts, particularly in the domains of developmental biology, cancer research, and epithelial-mesenchymal transition (EMT). By creating a knockout model, scientists can investigate the role of SNAI3 in regulating gene expression, cellular differentiation, and responses to external stimuli.
The key mechanism by which these cell lines function lies in the loss of SNAI3-mediated transcriptional repression, allowing for the study of pathways and cellular processes that are normally suppressed by SNAI3 activity. This functionality offers a unique opportunity to explore the implications of SNAI3 deletion in cellular behaviors such as migration, invasion, and signaling pathways involved in tumorigenesis or tissue regeneration.
From a scientific perspective, SNAI3 Gene Knockout Cell Lines are invaluable for high-throughput screening applications, as well as for validating targets in therapeutic development. Their unique ability to mimic the loss-of-function mutations found in various cancers makes them particularly relevant for preclinical studies. Additionally, they provide a robust platform for testing novel drugs aimed at restoring normal cellular function in SNAI3-deficient environments.
What sets our SNAI3 Gene Knockout Cell Lines apart from alternatives is the precision of the genetic modification and the comprehensive validation processes we employ, ensuring high stability and reproducibility for research applications. Moreover, our commitment to quality assurance means that our cell lines are free from contamination and exhibit consistent growth characteristics, crucial for successful experimental outcomes.
Ultimately, these cell lines represent a significant advancement in the toolkit available to researchers and clinicians, facilitating deeper insights into the underlying mechanisms of diseases and the potential for developing targeted interventions. Our company prides itself on its extensive experience in the field of genetic engineering, providing high-quality biological products designed to meet the evolving needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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