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SMYD4 Knockout Cell Lines

Gene: SMYD4

Official Full Name: SET and MYND domain containing 4provided by HGNC

Gene Summary: Predicted to enable histone deacetylase binding activity. Involved in heart development. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30730 SMYD4 Knockout cell line (HeLa) Human SMYD4 1:3~1:6 Negative Online Inquiry
KO30731 SMYD4 Knockout cell line (HCT 116) Human SMYD4 1:2~1:4 Negative Online Inquiry
KO30732 SMYD4 Knockout cell line (HEK293) Human SMYD4 1:3~1:6 Negative Online Inquiry
KO30733 SMYD4 Knockout cell line (A549) Human SMYD4 1:3~1:4 Negative Online Inquiry

Background

SMYD4 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to study the SMYD4 gene, known for its role in epigenetic regulation and implications in oncogenesis. By employing CRISPR/Cas9 technology, these cell lines allow researchers to investigate the biological consequences of SMYD4 loss-of-function, thereby elucidating its potential function in cancer progression and other pathophysiological processes.

The primary mechanism of the SMYD4 gene knockout involves the targeted disruption of the gene's coding sequence, resulting in the elimination of its protein product. This enables researchers to delineate the gene’s contribution to cellular pathways such as methylation processes, chromatin organization, and gene expression regulation. The SMYD4 knockout models are invaluable for understanding the gene's involvement in various diseases, offering insights into targeted therapeutic strategies.

In the scientific community, SMYD4 has emerged as a gene of interest due to its correlation with tumorigenesis and epigenetic alterations in several cancer types. The availability of knockout cell lines facilitates high-throughput screening, functional assays, and validation of potential drug candidates, making them essential tools for basic research and drug development.

What sets our SMYD4 Gene Knockout Cell Lines apart from competitors is the meticulous quality control measures taken during their production, ensuring consistency, reliability, and reproducibility in experimental outcomes. Additionally, these cell lines are readily available for diverse applications in academia and industry, providing researchers with a time-efficient resource to advance their studies.

Our commitment to delivering innovative biological tools is backed by a dedicated team of experts in molecular biology and genetic engineering. We pride ourselves on empowering researchers and clinicians with high-quality products that facilitate groundbreaking discoveries in the field of epigenetics and beyond.

Please note that all services are for research use only. Not intended for any clinical use.

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