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SMIM43 Knockout Cell Lines

Gene: SMIM43

Official Full Name: small integral membrane protein 43provided by HGNC

Gene Summary: Enables transmembrane transporter binding activity. Predicted to be involved in mesendoderm development. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26519 SMIM43 Knockout cell line (HeLa) Human SMIM43 1:3~1:6 Negative Online Inquiry
KO26520 SMIM43 Knockout cell line (HCT 116) Human SMIM43 1:2~1:4 Negative Online Inquiry
KO26521 SMIM43 Knockout cell line (A549) Human SMIM43 1:3~1:4 Negative Online Inquiry

Background

SMIM43 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically designed to functionally knock out the SMIM43 gene, which is implicated in various cellular processes, including regulation of hematopoiesis and cellular signaling pathways. By using CRISPR-Cas9 technology, these cell lines provide researchers with a powerful tool to explore the role of SMIM43 in normal physiology and disease states.

The primary function of SMIM43 Gene Knockout Cell Lines lies in their ability to help determine the biological impact of the SMIM43 gene. In the absence of this gene, researchers can observe changes in gene expression profiles, protein interactions, and cellular behaviors. This knockout model establishes a pivotal mechanism for unraveling the gene's contribution to diseases, potentially leading to innovative therapeutic strategies. It serves as a reliable model system for studying the molecular pathology associated with hematological disorders, offering insights into targeted genetic therapies.

Scientifically, the development of SMIM43 Gene Knockout Cell Lines is significant for both fundamental research and translational studies. In clinical settings, understanding the function of SMIM43 can aid in elucidating the molecular mechanisms underlying specific hematologic conditions, thus paving the way for novel diagnostic and therapeutic modalities.

Compared to alternative gene editing approaches, our SMIM43 Gene Knockout Cell Lines offer enhanced specificity and efficiency, minimizing off-target effects and facilitating more reliable experimental outcomes. The cell lines come with comprehensive supporting documentation and well-characterized validation, underscoring their value to researchers seeking consistency and reproducibility.

For researchers and clinicians, the SMIM43 Gene Knockout Cell Lines represent a transformative asset in the quest to answer pressing biological questions. The ability to manipulate this specific gene functions not only furthers our understanding of cellular dynamics but also enhances the capacity for therapeutic intervention in related diseases.

With a steadfast commitment to quality and innovation, our company is at the forefront of developing pioneering biological products that empower researchers in their scientific endeavors, ensuring the provision of cutting-edge tools like our SMIM43 Gene Knockout Cell Lines that drive discoveries forward.

Please note that all services are for research use only. Not intended for any clinical use.

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